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  2. Factor V Leiden - Wikipedia

    en.wikipedia.org/wiki/Factor_V_Leiden

    Factor V Leiden (rs6025 or F5 p.R506Q [1]) is a variant (mutated form) of human factor V (one of several substances that helps blood clot), which causes an increase in blood clotting (hypercoagulability).

  3. Activated protein C resistance test - Wikipedia

    en.wikipedia.org/wiki/Activated_protein_C...

    The activated protein C resistance (APCR) test is a coagulation test used in the evaluation and diagnosis of activated protein C (APC) resistance, a form of hypercoagulability.

  4. Activated protein C resistance - Wikipedia

    en.wikipedia.org/wiki/Activated_protein_C_resistance

    APC resistance is the inability of protein C to cleave Factor Va and/or Factor VIIIa, which allows for longer duration of thrombin generation and may lead to a hypercoagulable state. This may be hereditary or acquired. [4] The best known and most common hereditary form is Factor V Leiden, which is responsible for more than 95% of cases. [5]

  5. What you need to know about factor V Leiden - a blood ... - AOL

    www.aol.com/news/know-factor-v-leiden-blood...

    Factor V Leiden is an inherited blood clotting disorder. It can cause life-threatening clots in the body and complications during pregnancy. What you need to know about factor V Leiden - a blood ...

  6. Thrombophilia - Wikipedia

    en.wikipedia.org/wiki/Thrombophilia

    The minor ("type 2") thrombophilias are much more common. Factor V Leiden is present in 5% of the population of Northern European descent, but much rarer in those of Asian or African extraction. In people with thrombosis, 10% have factor V Leiden. In those who are referred for thrombophilia testing, 30–50% have the defect.

  7. Venous thrombosis - Wikipedia

    en.wikipedia.org/wiki/Venous_thrombosis

    American evidence-based clinical guidelines were published in 2016 for the treatment of VTE. [42] In the UK, guidelines by the National Institute for Health and Care Excellence (NICE) were published in 2012, updated in 2020. [43] These guidelines do not cover rare forms of thrombosis, for which an individualized approach is often needed. [5]

  8. Coagulopathy - Wikipedia

    en.wikipedia.org/wiki/Coagulopathy

    Coagulopathy (also called a bleeding disorder) is a condition in which the blood's ability to coagulate (form clots) is impaired. [1] This condition can cause a tendency toward prolonged or excessive bleeding (bleeding diathesis), which may occur spontaneously or following an injury or medical and dental procedures.

  9. Factor V - Wikipedia

    en.wikipedia.org/wiki/Factor_V

    Coagulation factor V (Factor V), also less commonly known as proaccelerin or labile factor, is a protein involved in coagulation, encoded, in humans, by F5 gene. [5] In contrast to most other coagulation factors, it is not enzymatically active but functions as a cofactor . [ 5 ]

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