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Pepsin is expressed as a zymogen called pepsinogen, whose primary structure has an additional 44 amino acids compared to the active enzyme. In the stomach, gastric chief cells release pepsinogen. This zymogen is activated by hydrochloric acid (HCl), which is released from parietal cells in the stomach lining.
n/a Ensembl ENSG00000229859 n/a UniProt P0DJD8 n/a RefSeq (mRNA) NM_001079807 n/a RefSeq (protein) NP_001073275 n/a Location (UCSC) Chr 11: 61.2 – 61.21 Mb n/a PubMed search n/a Wikidata View/Edit Human Pepsinogen 3, group I (pepsinogen A) is a protein that in humans is encoded by the PGA3 gene. Function This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the ...
A gastric chief cell, peptic cell, or gastric zymogenic cell is a type of gastric gland cell that releases pepsinogen and gastric lipase.It is the cell responsible for secretion of chymosin (rennin) in ruminant animals and some other animals. [1]
Gastric juice is the combination of gastric gland secretions including the main component of hydrochloric acid (gastric acid), gastric lipase and pepsinogen. [4] Once in the stomach pepsinogen is changed by gastric acid to the digestive enzyme pepsin adding this enzyme to the gastric juice. [5]
The oxyntic gland contains the parietal cells that produce hydrochloric acid and intrinsic factor, and chief cells that produce pepsinogen and gastric lipase. The pyloric gland is found in the pyloric region, the remaining 20 per cent of the stomach. The pyloric glands are mainly in the pyloric antrum. The pyloric gland secretes gastrin from ...
Really, the bad-for-you-foods we imagine when we think about food processing are actually ultra-processed foods such as frozen pizza, potato chips, ready-made meals, and cookies.
The food served on planes doesn’t have the best reputation at the best of times, ... But one unfortunate English translation has got people talking. Among the choices for a starter is ...
Progastricsin is an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa.