Ads
related to: alternative to tamoxifen for postmenopausal- Menopausal Relief
Learn more about Relizen, made to
reduce hot flashes & night sweats.
- Vaginal Atrophy Symptoms
Symptoms of a Hormonal Shift
What You Should Know
- Thermella Free Trial
Fast-Acting Hot Flash Relief*
Start Your 2-Week Free Trial Today.
- Intimacy During Menopause
Tips From Our Medical Advisor
Alyssa Dweck, MS, MD, FACOG
- Menopausal Relief
myalloy.com has been visited by 10K+ users in the past month
bywinona.com has been visited by 10K+ users in the past month
Search results
Results from the WOW.Com Content Network
Toremifene is approved for the treatment of metastatic breast cancer in postmenopausal women with estrogen receptor-positive or unknown-status tumors. [4] [6] This is its only approved use in the United States. [4] It shows equivalent effectiveness to tamoxifen for this indication.
Tamoxifen is also thought to lower the risk of breast cancer in those who have a predisposition or at risk. [9] Tamoxifen may be used in pre and postmenopausal women. [10] Toremifene is a similar SERM drug to tamoxifen, but is less common and only approved for treatment of metastatic cancer. Toremifene is generally prescribed once tamoxifen is ...
Exemestane is indicated for the adjuvant treatment of postmenopausal women with estrogen-receptor positive early breast cancer who have received two to three years of tamoxifen and are switched to it for completion of a total of five consecutive years of adjuvant hormonal therapy. [3] US FDA approval was in October 1999. [4]
One of the phase 3 trials was a randomized, double-blind placebo-controlled trial in 826 post-menopausal women. [15] The trial patients were required to have one or more symptom of vulvovaginal atrophy (VVA) that was moderate or severe in nature with fewer than 5% of cells that were superficial when examined by a vaginal smear and a vaginal pH ...
Sivifene (A-007) was initially thought to be a SERM due to its structural similarity to tamoxifen but it was subsequently found not to bind to the estrogen receptor (ER). [8] Tesmilifene (DPPE; YMB-1002, BMS-217380-01) is also structurally related to tamoxifen but similarly does not bind to the ER and is not a SERM. [9] [10]
Toremifene has been shown to be compatible with tamoxifen, and in 1996 it was approved for use in the treatment of breast cancer in postmenopausal women. [ 36 ] Raloxifene originally failed as a breast cancer drug due to its poor performance in comparison to tamoxifen in the laboratory [ 19 ] but the estrogenic effects of raloxifene on bone led ...
Ads
related to: alternative to tamoxifen for postmenopausalmyalloy.com has been visited by 10K+ users in the past month
bywinona.com has been visited by 10K+ users in the past month