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Tamoxifen treatment of postmenopausal women is associated with beneficial effects on serum lipid profiles. However, long-term data from clinical trials have failed to demonstrate a cardioprotective effect. [52] For some women, tamoxifen can cause a rapid increase in triglyceride concentration in the blood.
Tamoxifen is also thought to lower the risk of breast cancer in those who have a predisposition or at risk. [9] Tamoxifen may be used in pre and postmenopausal women. [10] Toremifene is a similar SERM drug to tamoxifen, but is less common and only approved for treatment of metastatic cancer. Toremifene is generally prescribed once tamoxifen is ...
Hormone replacement therapy could be a major key to unlocking health benefits for women going through menopause, according to new research.. A study published Aug. 29 in the journal JAMA Network ...
[5] [6] Tamoxifen treatment is also used for the treatment of osteoporosis and blood lipids in postmenopausal women. Adverse effects of tamoxifen include hot flashes and an increase in the risk of developing endometrial cancer compared to women of similar age. [6] [4] Toremifene, a chlorinated tamoxifen derivative developed to avoid hepatic ...
In fact, there’s one nutrient that Dr. Weil says post-menopausal women need less of: iron. “After menopause, women no longer bleed every month with their periods, so their iron levels are higher.
Premature menopause can occur if the ovaries are surgically removed, as can be done to treat ovarian or uterine cancer. Demographically, the vast majority of data available is in postmenopausal American women with concurrent pre-existing conditions and an average age of over 60 years. [18]
The average American woman will reach menopause at age 52, but onset age can range from about 45 to 58, per the Office on Women’s Health in the U.S. Department of Health and Human Services.
Antiestrogens include selective estrogen receptor modulators (SERMs) like tamoxifen, clomifene, and raloxifene, the ER silent antagonist and selective estrogen receptor degrader (SERD) fulvestrant, [6] [7] aromatase inhibitors (AIs) like anastrozole, and antigonadotropins including androgens/anabolic steroids, progestogens, and GnRH analogues.