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[21] [22] In general, gram negative bacteria enter the bloodstream from infections in the respiratory tract, genitourinary tract, gastrointestinal tract, or hepatobiliary system. Gram-negative bacteremia occurs more frequently in elderly populations (65 years or older) and is associated with higher morbidity and mortality in this population. [23]
Septic shock is low blood pressure due to sepsis that does not improve after fluid replacement. [9] Sepsis is caused by many organisms including bacteria, viruses, and fungi. [10] Common locations for the primary infection include the lungs, brain, urinary tract, skin, and abdominal organs. [2]
Clinical diagnosis of invasive H. influenzae infection (infection that has spread to the bloodstream and internal tissues) is typically confirmed by bacterial culture, latex particle agglutination tests, or polymerase chain reaction tests on clinical samples obtained from an otherwise sterile body site.
A blood culture is a medical laboratory test used to detect bacteria or fungi in a person's blood.Under normal conditions, the blood does not contain microorganisms: their presence can indicate a bloodstream infection such as bacteremia or fungemia, which in severe cases may result in sepsis.
Group B streptococcal infection, also known as Group B streptococcal disease or just Group B strep infection, is the infectious disease caused by the bacterium Streptococcus agalactiae. Streptococcus agalactiae is the most common human pathogen belonging to group B of the Lancefield classification of streptococci —hence the name of group B ...
The bacteria also can cause a bloodstream infection with symptoms like chills, fatigue, cold hands and feet, rapid breathing, diarrhea, or, in later stages, a dark purple rash.
Staphylococcus aureus is a leading cause of bloodstream infections throughout much of the industrialized world. [43] Infection is generally associated with breaks in the skin or mucosal membranes due to surgery, injury, or use of intravascular devices such as cannulas, hemodialysis machines, or hypodermic needles.
If the bacteria enters the bloodstream, the infection can become severe and life-threatening, and is called an invasive GAS (iGAS). [2] [3] Infection of GAS may spread through direct contact with mucus or sores on the skin. [2] GAS infections can cause over 500,000 deaths per year. [4]
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