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Anticonvulsant. Anticonvulsants (also known as antiepileptic drugs, antiseizure drugs, or anti-seizure medications (ASM)) are a diverse group of pharmacological agents used in the treatment of epileptic seizures. [ 1 ] Anticonvulsants are also increasingly being used in the treatment of bipolar disorder [ 2 ][ 3 ] and borderline personality ...
Retigabine (INN) or ezogabine (USAN) is an anticonvulsant used as an adjunctive treatment for partial epilepsies in treatment-experienced adult patients. [ 2 ] The drug was developed by Valeant Pharmaceuticals and GlaxoSmithKline. It was approved by the European Medicines Agency under the trade name Trobalt on March 28, 2011, and by the United ...
140,000 (2021) [ 9 ] Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. [ 10 ] An epileptic seizure is the clinical manifestation of an abnormal, excessive, and synchronized electrical discharge in the neurons. [ 1 ] The occurrence of two or more unprovoked seizures defines epilepsy. [ 11 ]
Status epilepticus (SE), or status seizure, is a medical condition consisting of a single seizure lasting more than 5 minutes, or 2 or more seizures within a 5-minute period without the person returning to normal between them. [3][1] Previous definitions used a 30-minute time limit. [2] The seizures can be of the tonic–clonic type, with a ...
Neurology, Psychiatry. In the field of neurology, temporal lobe epilepsy is an enduring brain disorder that causes unprovoked seizures from the temporal lobe. Temporal lobe epilepsy is the most common type of focal onset epilepsy among adults. [ 1 ] Seizure symptoms and behavior distinguish seizures arising from the medial temporal lobe from ...
A seizure is a period of symptoms due to abnormally excessive or synchronous neuronal activity in the brain. [6] Outward effects vary from uncontrolled shaking movements involving much of the body with loss of consciousness (tonic-clonic seizure), to shaking movements involving only part of the body with variable levels of consciousness (focal seizure), to a subtle momentary loss of awareness ...
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), also known as multiorgan hypersensitivity, has been reported in patients taking antiepileptic drugs, including gabapentin. HORIZANT ...
Tiagabine is primarily used as an anticonvulsant in the treatment of epilepsy as a supplement. Although the exact mechanism by which Tiagabine exerts its antiseizure effect is unknown, it is thought to be related to its ability to increase the activity of gamma aminobutyric acid (GABA), the central nervous system's major inhibitory ...