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Cyanide is a potent cytochrome c oxidase (COX, a.k.a. Complex IV) inhibitor, causing asphyxiation of cells. As such, cyanide poisoning is a form of histotoxic hypoxia, because it interferes with the ability of cells to take or use oxygen via oxidative phosphorylation. [ 25 ]: 1475. Specifically, cyanide binds to the heme a3-CuB binuclear center ...
Strychnos toxifera, the Strychnos species which is the principal source of 'calabash curare' and its main active constituent, the alkaloid toxiferine. Curare (/ kʊˈrɑːri / or / kjʊˈrɑːri /; kuu-RAH-ree or kyuu-RAH-ree) is a common name for various alkaloid arrow poisons originating from plant extracts.
Not to be confused with anecdote. An antidote is a substance that can counteract a form of poisoning. [ 1 ] The term ultimately derives from the Greek term φάρμακον ἀντίδοτον (pharmakon antidoton), " (medicine) given as a remedy". Antidotes for anticoagulants are sometimes referred to as reversal agents.
The primary antidote to brodifacoum poisoning is immediate administration of vitamin K 1 (dosage for humans: initially slow intravenous injections of 10–25 mg repeated at 3–6 hours until normalisation of the prothrombin time; then 10 mg orally four times daily as a "maintenance dose"). It is an extremely effective antidote, provided the ...
Linux. WW: 22 May 2014. Genre (s) Action role-playing. Mode (s) Single-player. The Witcher 2: Assassins of Kings (Polish: Wiedźmin 2: Zabójcy królów) is a 2011, action role-playing video game developed by CD Projekt Red, based on The Witcher series of fantasy novels authored by Andrzej Sapkowski. It is a sequel to the 2007 game, The Witcher ...
There is no antidote for strychnine poisoning. [5] Strychnine poisoning demands aggressive management with early control of muscle spasms, intubation for loss of airway control, toxin removal (decontamination), intravenous hydration and potentially active cooling efforts in the context of hyperthermia as well as hemodialysis in kidney failure (strychnine has not been shown to be removed by ...
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Domoic acid (DA) is a kainic acid-type neurotoxin that causes amnesic shellfish poisoning (ASP). [1] It is produced by algae and accumulates in shellfish , sardines , and anchovies . When sea lions, otters, cetaceans, humans, and other predators eat contaminated animals, poisoning may result.