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Centromere Definition. The centromere is the point on a chromosome where mitotic spindle fibers attach to pull sister chromatids apart during cell division. When a cell seeks to reproduce itself, it must first make a complete copy of each of its chromosomes, to ensure that their daughter cell receives a full complement of the parent cell’s DNA.
The physical role of the centromere is to act as the site of assembly of the kinetochores – a highly complex multiprotein structure that is responsible for the actual events of chromosome segregation – i.e. binding microtubules and signaling to the cell cycle machinery when all chromosomes have adopted correct attachments to the spindle, so that...
The centromere appears as a constricted region of a chromosome and plays a key role in helping the cell divide up its DNA during division (mitosis and meiosis). Specifically, it is the region where the cell’s spindle fibers attach.
When a cell divides, the centromere, which resembles a constrictive area of a chromosome, is fundamental in assisting in the division of the DNA within the cell (mitosis and meiosis) during the metaphase stage.
A centromere is a specialized location in the DNA that functions as the control centre of cell division and is maintained, unchanged, across generations of cells. It is characterized by a special protein, called centromeric protein A (CENP-A), which marks the centromere and mobilizes other players necessary for cell division.
A centromere is a region on a chromosome that joins sister chromatids. Sister chromatids are double-stranded, replicated chromosomes that form during cell division. The primary function of the centromere is to serve as a place of attachment for spindle fibers during cell division.
A centromere is a constricted region of DNA or a structure in a chromosome, which plays an essential role in the segregation of chromosomes during the process of the cell cycle in eukaryotic cells. Let’s learn more about the centromere along with its structure, functions and different types of the centromere. Table of Contents.
The centromere is the genetic locus that specifies the site of kinetochore assembly, where the chromosome will attach to the kinetochore microtubule. The pericentromere is the physical region responsible for the geometry of bi-oriented sister kinetochores in metaphase.
Centromere, structure in a chromosome that holds together the two chromatids (the daughter strands of a replicated chromosome). The centromere is the point of attachment of the kinetochore, a structure to which the microtubules of the mitotic spindle become anchored.
Scientists now appreciate that the centromere is a region of specialized chromatin found within each constricted chromosome that provides the foundation for kinetochore assembly and serves as a...