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Senescence (/ sɪˈnɛsəns /) or biological aging is the gradual deterioration of functional characteristics in living organisms. Whole organism senescence involves an increase in death rates or a decrease in fecundity with increasing age, at least in the later part of an organism's life cycle. [ 1 ][ 2 ] However, the resulting effects of ...
Sentience is an important concept in ethics, as the ability to experience happiness or suffering often forms a basis for determining which entities deserve moral consideration, particularly in utilitarianism. [ 4 ] In Asian religions, the word "sentience" has been used to translate a variety of concepts. In science fiction, the word "sentience ...
Cellular senescence is a phenomenon characterized by the cessation of cell division. [ 1 ][ 2 ][ 3 ] In their experiments during the early 1960s, Leonard Hayflick and Paul Moorhead found that normal human fetal fibroblasts in culture reach a maximum of approximately 50 cell population doublings before becoming senescent. [ 4 ][ 5 ][ 6 ] This ...
e. Psychology is the scientific study of mind and behavior. [ 1 ][ 2 ] Its subject matter includes the behavior of humans and nonhumans, both conscious and unconscious phenomena, and mental processes such as thoughts, feelings, and motives. Psychology is an academic discipline of immense scope, crossing the boundaries between the natural and ...
Cognitive reserve is the mind's and brain's resistance to damage of the brain. The mind's resilience is evaluated behaviorally, whereas the neuropathological damage is evaluated histologically, although damage may be estimated using blood-based markers and imaging methods. There are two models that can be used when exploring the concept of ...
Wilhelm Maximilian Wundt (/ wʊnt /; German: [vʊnt]; 16 August 1832 – 31 August 1920) was a German physiologist, philosopher, and professor, one of the fathers of modern psychology. Wundt, who distinguished psychology as a science from philosophy and biology, was the first person ever to call himself a psychologist. [ 1 ]
The hallmarks of aging are the types of biochemical changes that occur in all organisms that experience biological aging and lead to a progressive loss of physiological integrity, impaired function and, eventually, death. They were first listed in a landmark paper in 2013 [1] to conceptualize the essence of biological aging and its underlying ...
Life extension is the concept of extending the human lifespan, either modestly through improvements in medicine or dramatically by increasing the maximum lifespan beyond its generally-settled biological limit of around 125 years. [ 1 ] Several researchers in the area, along with "life extensionists", " immortalists ", or " longevists " (those ...