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Targeted drug delivery. Targeted drug delivery, sometimes called smart drug delivery, [1] is a method of delivering medication to a patient in a manner that increases the concentration of the medication in some parts of the body relative to others. This means of delivery is largely founded on nanomedicine, which plans to employ nanoparticle ...
Within the broad field of drug delivery, the development of stimuli-responsive drug delivery systems has created the ability to tune drug delivery systems to achieve more controlled dosing and targeted specificity based on material response to exogenous and endogenous stimuli. Endogenous stimuli consist of chemical, biological, and physical ...
Drug delivery is a concept heavily integrated with dosage form and route of administration, the latter sometimes being considered part of the definition. [9] While route of administration is often used interchangeably with drug delivery, the two are separate concepts. Route of administration refers to the path a drug takes to enter the body ...
Chemotactic drug-targeting. Targeted drug delivery is one of many ways researchers seek to improve drug delivery systems' overall efficacy, safety, and delivery. Within this medical field is a special reversal form of drug delivery called chemotactic drug targeting. [1][2] By using chemical agents to help guide a drug carrier to a specific ...
Drug delivery to the brain. Drug delivery to the brain is the process of passing therapeutically active molecules across the blood–brain barrier into the brain. This is a complex process that must take into account the complex anatomy of the brain as well as the restrictions imposed by the special junctions of the blood–brain barrier.
pH-responsive tumor-targeted drug delivery is a specialized form of targeted drug delivery that utilizes nanoparticles to deliver therapeutic drugs directly to cancerous tumor tissue while minimizing its interaction with healthy tissue. [ 1] Scientists have used drug delivery as a way to modify the pharmacokinetics and targeted action of a drug ...
Enhanced drug uptake using acoustic targeted drug delivery. Delivering chemotherapy to brain cancer cells and various drugs to other tissues is called acoustic targeted drug delivery. [6] These procedures generally use high frequency ultrasound (1–10 MHz) and a range of intensities (0–20 W/cm 2). The acoustic energy is focused on the tissue ...
In the field of drug discovery, retrometabolic drug design is a strategy for the design of safer drugs either using predictable metabolism to an inactive moiety or using targeted drug delivery approaches. The phrase retrometabolic drug design was coined by Nicholas Bodor. [1] The method is analogous to retrosynthetic analysis where the ...