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William Coley was born on January 12, 1862, in Saugatuck, a neighborhood of Westport, Connecticut. His parents were Horace Bradley Coley and Clarina B. Wakeman. He received his bachelor's degree in Classics from Yale University and his medical degree from Harvard Medical School in 1888.
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The hospital appointed as an attending surgeon William B. Coley, who pioneered an early form of immunotherapy to eradicate tumors. [6] Rose Hawthorne, daughter of author Nathaniel Hawthorne, trained there in the summer of 1896 before founding her own order, Dominican Sisters of Hawthorne. [7]
1893 – Use of live bacteria and bacterial lysates to treat tumors – "Coley's Toxins", based on Busch and Fehleisen experiences (William B. Coley) 1894 – Bacteriolysis (Richard Pfeiffer) 1896 – An antibacterial, heat-labile serum component is described (Jules Bordet) 1900 – Antibody formation theory (Paul Ehrlich)
His research was honored with the 1993 Cancer Research Institute William B. Coley Award. Harvard called Wiley "one of the most influential biologists of his generation." In 1999, Wiley and another Harvard professor, Jack L. Strominger, won the Japan Prize for their discoveries of how the immune system protects humans from infections. [13]
Coley's toxins (also called Coley's toxin, [1] Coley's vaccine, [2] Coley vaccine, Coley's fluid or mixed bacterial vaccine) is a mixture containing toxins filtered from killed bacteria of species Streptococcus pyogenes and Serratia marcescens, named after William Coley, a surgical oncologist at the Hospital for Special Surgery who developed the mixture in the late 19th century as a treatment ...
The William B. Coley Award for Distinguished Research in Basic and Tumor Immunology is presented annually by the Cancer Research Institute, to scientists [1] who have made outstanding achievements in the fields of basic and tumor immunology and whose work has deepened our understanding of the immune system's response to disease, including cancer.
William B. Coley Award: Cancer Research Institute: Outstanding achievements in the fields of basic and tumor immunology and work that has deepened our understanding of the immune system's response to disease, including cancer United States: William B. Graham Prize for Health Services Research: Baxter International: Contributions to health care ...