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There are characteristic pathologic findings of acute inflammation and thrombosis (clotting) of arteries and veins of the hands and feet (the lower limbs being more common). The mechanisms underlying Buerger's disease are still largely unknown, but smoking and tobacco consumption are major factors associated with it.
Both active or passive smoking may bring harm to the vascular system. [15] For instance, cigarette smoking, cannabinoids and smokeless tobacco use were all found to raise blood pressure and increase the risk of stroke. [15] Moreover, cigar and cigarette smoking may also cause arterial stiffness. [15]
This is an accepted version of this page This is the latest accepted revision, reviewed on 1 February 2025. Circumstances, mechanisms, and factors of tobacco consumption on human health "Health effects of smoking" and "Dangers of smoking" redirect here. For cannabis, see Effects of cannabis. For smoking crack cocaine, see Crack cocaine § Health issues. "Smoking and health" redirects here. For ...
Arterial thromboembolism (ATE) is a less common but more severe form of thromboembolism, which can affect various organs, such as the brain, heart, kidneys, limbs, and mesentery. ATE can cause life-threatening conditions, such as stroke, myocardial infarction, acute kidney injury, limb ischemia, and mesenteric ischemia.
Thrombophilia screening in people with arterial thrombosis is generally regarded as unrewarding and is generally discouraged, [12] except possibly for unusually young patients (especially when precipitated by smoking or use of estrogen-containing hormonal contraceptives) and those in whom revascularization, such as coronary arterial bypass ...
An arterial embolism is caused by one or more emboli getting stuck in an artery and blocking blood flow, causing ischemia, possibly resulting in infarction with tissue death . [2] Individuals with arterial thrombosis or embolism often develop collateral circulation to compensate for the loss of arterial flow.
Peripheral artery disease most commonly affects the legs, but other arteries may also be involved, such as those of the arms, neck, or kidneys. [4] [17] Peripheral artery disease (PAD) is a form of peripheral vascular disease. Vascular refers to both the arteries and veins within the body. PAD differs from peripheral veinous disease. PAD means ...
Alternatively, arterial occlusion occurs as a consequence of embolism of blood clots originating from the heart ("cardiogenic" emboli). The most common cause is atrial fibrillation, which causes a blood stasis within the atria with easy thrombus formation, but blood clots can develop inside the heart for other reasons too as infective endocarditis.