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Individuals who have undergone a transplant, HIV, cancer or use corticosteroids commonly develop candida of the mouth and oral cavity. Other risk factors are dentures and tongue piercing . The typical signs are a white patch that may be associated with burning, soreness, irritation or a white cheesy-like appearance.
Oral submucous fibrosis (OSF) is a chronic, complex, premalignant (1% transformation risk) condition of the oral cavity, characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues (the lamina propria and deeper connective tissues).
P11-4 is a self-assembling β-peptide. It builds a 3-D bio-matrix with binding sites for Calcium-ions serving as nucleation point for hydroxyapatite (tooth mineral) formation. The high affinity to tooth mineral is based on matching distances of Ca-ion binding sites on P11-4 and Ca spacing in the crystal lattice of hydroxyapatite.
Mineralized tissues combine stiffness, low weight, strength and toughness due to the presence of minerals (the inorganic part) in soft protein networks and tissues (the organic part). [ 1 ] [ 2 ] There are approximately 60 different minerals generated through biological processes, but the most common ones are calcium carbonate found in mollusk ...
The primary mineral is hydroxyapatite, which is a crystalline calcium phosphate. [4] Enamel is formed on the tooth while the tooth develops within the jaw bone before it erupts into the mouth. Once fully formed, enamel does not contain blood vessels or nerves, and is not made of cells.
More simply, epulis fissuratum is where excess folds of firm tissue form inside the mouth, as a result of rubbing on the edge of dentures that do not fit well. It is a harmless condition and does not represent oral cancer. Treatment is by simple surgical removal of the lesion, and also by adjustment of the denture or provision of a new denture.
Gingival enlargement has a multitude of causes. The most common is chronic inflammatory gingival enlargement, when the gingivae are soft and discolored. This is caused by tissue edema and infective cellular infiltration caused by prolonged exposure to bacterial plaque, and is treated with conventional periodontal treatment, such as scaling and root planing.
Poly-MVA is promoted with claims that it can treat a variety of human diseases, including cancer and HIV/AIDS. [1] The promotional effort is supported by customer testimonials, but there is no medical evidence that Poly-MVA confers any health benefit and some concern it may inhibit the effectiveness of mainstream cancer treatments if used at the same time.