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Hydrazine can be protonated to form various solid salts of the hydrazinium cation [N 2 H 5] +, by treatment with mineral acids. A common salt is hydrazinium hydrogensulfate, [N 2 H 5] + [HSO 4] −. [60] Hydrazinium hydrogensulfate was investigated as a treatment of cancer-induced cachexia, but proved ineffective. [61]
Later randomized controlled trials failed to find any improvement in survival, [27] [28] For example, in a trial of the treatment of advanced lung cancer, with either cisplatin and vinblastine or these drugs plus hydrazine sulfate, saw complete tumor regression in 4% of the hydrazine group, versus 3% in the control group, and tumor progression ...
According to the American Cancer Society, "evidence does not support claims that goldenseal is effective in treating cancer or other diseases. Goldenseal can have toxic side effects, and high doses can cause death." [76] Gotu kola – a swamp plant native to parts of Asia and Africa. Supplements made from it are promoted as cancer treatment ...
The use of sedating drugs alongside hydroxyzine can cause oversedation and confusion if administered at high doses—any form of hydroxyzine treatment alongside sedatives should be done under the supervision of a doctor. [28] [25] Because of the potential for more severe side effects, this drug is on the list to avoid in the elderly. [29]
Hepatotoxicity, dermatological side effects, and abuse potential. [7] Aminopyrine: 1999 France, Thailand Risk of agranulocytosis and severe acne. [3] Amobarbital: 1980 Norway Risk of barbiturate toxicity. [3] Amoproxan: 1970 France Dermatologic and ophthalmic toxicity. [3] Anagestone acetate: 1969 Germany Animal carcinogenicity. [3] Antrafenine ...
This is a list of drugs and substances that are known or suspected to cause Stevens–Johnson syndrome This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources .
Hydrazine and its methyl derivatives are toxic but LD50 values have not been reported. [17] It is a precursor to dimethylnitrosamine, which is carcinogenic. [18] According to scientific data, usage of UDMH in rockets at Baikonur Cosmodrome has had adverse effects on the environment. [19]
Hydrazines (R 2 N−NR 2) are a class of chemical compounds with two nitrogen atoms linked via a covalent bond and which carry from one up to four alkyl or aryl substituents. . Hydrazines can be considered as derivatives of the inorganic hydrazine (H 2 N−NH 2), in which one or more hydrogen atoms have been replaced by hydrocarbon grou