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  2. Somatic evolution in cancer - Wikipedia

    en.wikipedia.org/wiki/Somatic_evolution_in_cancer

    Cancer treatment drugs pose a strong selective force on all types of cells in tumors, including cancer stem cells, which would be forced to evolve resistance to the treatment. Cancer stem cells do not always have to have the highest resistance among the cells in the tumor to survive chemotherapy and re-emerge afterwards.

  3. Phylogenetics - Wikipedia

    en.wikipedia.org/wiki/Phylogenetics

    Phylogenetics is a component of systematics that uses similarities and differences of the characteristics of species to interpret their evolutionary relationships and origins. Phylogenetics focuses on whether the characteristics of a species reinforce a phylogenetic inference that it diverged from the most recent common ancestor of a taxonomic ...

  4. Tumour heterogeneity - Wikipedia

    en.wikipedia.org/wiki/Tumour_heterogeneity

    The cancer stem cell model asserts that within a population of tumour cells, there is only a small subset of cells that are tumourigenic (able to form tumours). These cells are termed cancer stem cells (CSCs), and are marked by the ability to both self-renew and differentiate into non-tumourigenic progeny. The CSC model posits that the ...

  5. List of phylogenetics software - Wikipedia

    en.wikipedia.org/wiki/List_of_phylogenetics_software

    Explore, manipulate, analyze, and simulate phylogenetic objects (alignments, trees, and MCMC logs) J.W. Brown, J.F. Walker, and S.A. Smith POY A phylogenetic analysis program that supports multiple kinds of data and can perform alignment and phylogeny inference. A variety of heuristic algorithms have been developed for this purpose

  6. Phylogenetic tree - Wikipedia

    en.wikipedia.org/wiki/Phylogenetic_tree

    A phylogenetic tree, phylogeny or evolutionary tree is a graphical representation which shows the evolutionary history between a set of species or taxa during a specific time. [ 1 ] [ 2 ] In other words, it is a branching diagram or a tree showing the evolutionary relationships among various biological species or other entities based upon ...

  7. History of cancer - Wikipedia

    en.wikipedia.org/wiki/History_of_cancer

    The first cause of cancer was identified by British surgeon Percivall Pott, who discovered in 1775 that cancer of the scrotum was a common disease among chimney sweeps. [ citation needed ] The work of other individual physicians led to various insights, but when physicians started working together they could draw firmer conclusions.

  8. Molecular phylogenetics - Wikipedia

    en.wikipedia.org/wiki/Molecular_phylogenetics

    Molecular phylogenetics (/ m ə ˈ l ɛ k j ʊ l ər ˌ f aɪ l oʊ dʒ ə ˈ n ɛ t ɪ k s, m ɒ-, m oʊ-/ [1] [2]) is the branch of phylogeny that analyzes genetic, hereditary molecular differences, predominantly in DNA sequences, to gain information on an organism's evolutionary relationships. From these analyses, it is possible to determine ...

  9. Phylogenesis - Wikipedia

    en.wikipedia.org/wiki/Phylogenesis

    Taxonomy (Greek language τάξις, taxis = 'order', 'arrangement' + νόμος, nomos = 'law' or 'science') is the classification, identification and naming of organisms. . It is usually richly informed by phylogenetics, but remains a methodologically and logically distinct discipline.