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IL13RA2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Overview of all the structural information available in the PDB for UniProt: Q14627 (Interleukin-13 receptor subunit alpha-2) at the PDBe-KB. This article incorporates text from the United States National Library of Medicine, which is in the public ...
There is also another receptor that can bind IL-13: IL-13Rα2 encoded by the IL13RA2 gene. This binds IL-13 with very high affinity (and can therefore sequester it) but does not allow IL-4 binding. It acts as a negative regulator of both IL-13 and IL-4, however the mechanism of this is still undetermined. [3]
Schematic structure of an antibody–drug conjugate (ADC) Antibody–drug conjugates or ADCs are a class of biopharmaceutical drugs designed as a targeted therapy for treating cancer. [ 1 ] Unlike chemotherapy , ADCs are intended to target and kill tumor cells while sparing healthy cells.
Type II cytokine receptors, also commonly known as class II cytokine receptors, are transmembrane proteins that are expressed on the surface of certain cells. They bind and respond to a select group of cytokines including interferon type I, interferon type II, interferon type III.
57916 Ensembl ENSG00000240505 ENSMUSG00000010142 UniProt O14836 Q9ET35 RefSeq (mRNA) NM_012452 NM_021349 RefSeq (protein) NP_036584 NP_067324 Location (UCSC) Chr 17: 16.93 – 16.97 Mb Chr 11: 61.02 – 61.04 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B ...
The interleukin 4 receptor is a type I cytokine receptor.It is a heterodimer, that is, composed of two subunits. IL4R is the human gene coding for IL-4Rα, the subunit which combines with either common gamma chain (γc, forming the type I IL4 receptor) or with IL-13Rα1 (forming the type II IL4 receptor).
The interleukin-2 receptor alpha chain (also called Tac antigen, P55, and mainly CD25) is a protein involved in the assembly of the high-affinity interleukin-2 receptor, consisting of alpha (IL2RA), beta and the common gamma chain ().
12984 Ensembl ENSG00000100368 ENSMUSG00000071714 UniProt P32927 P26954 RefSeq (mRNA) NM_000395 NM_001287389 NM_007781 RefSeq (protein) NP_000386 NP_001274318 NP_031807 Location (UCSC) Chr 22: 36.91 – 36.94 Mb Chr 15: 78.17 – 78.19 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse CSF2RB (also known as cytokine receptor common subunit beta) is a common subunit to the following type ...
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