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It is a form of penicillin which is a salt of benzylpenicillin and the local anaesthetic agent procaine. [9] The salt has weak solubility, and is prepared as a suspension. Upon injection it forms a deposit within tissue (a "depot'), and the salt slowly dissolves into interstitial fluid - dissociating the two molecules into their bioactive forms over an extended pe
The β-lactam core structures. (A) A penam.(B) A carbapenam.(C) An oxapenam.(D) A penem.(E) A carbapenem.(F) A monobactam.(G) A cephem.(H) A carbacephem.(I) An oxacephem. This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class.
Panipenem/betamipron is a carbapenem antibiotic [1] marketed by Daiichi Sankyo Co. of Japan.It was launched in 1993, [2] under the brand name Carbenin. [3]It is a combination in which panipenem is the carbapenem antibiotic and betamipron inhibits renal uptake of panipenem [4] and so reduces its nephrotoxicity [5] (much like the imipenem/cilastatin combination).
Benzathine benzylpenicillin/procaine benzylpenicillin, sold under the brand name Bicillin C-R, is an antibiotic medication. [1] It contains the antibiotics benzathine benzylpenicillin (penicillin G benzathine) and procaine benzylpenicillin (penicillin G procaine).
For tropical ulcers it is used together with procaine benzylpenicillin for two to four weeks. [2] [8] It can be used in children and adults. [8] It can be applied as a soaked dressing or a bath. [2] Petroleum jelly may be used on the nails before soaking to prevent their discoloration. [1]
β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.
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It is a semi-synthetic analogue of the naturally occurring benzylpenicillin. Carbenicillin at high doses can cause bleeding. Carbenicillin at high doses can cause bleeding. Use of carbenicillin can cause hypokalemia by promoting potassium loss at the distal convoluted tubule of the kidney.