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In enzymology, a citrullinase (EC 3.5.1.20) is an enzyme that catalyzes the chemical reaction. L-citrulline + H 2 O L-ornithine + CO 2 + NH 3. Thus, the two substrates of this enzyme are L-citrulline and H 2 O, whereas its 3 products are L-ornithine, CO 2, and NH 3.
The organic compound citrulline is an α-amino acid. [2] Its name is derived from citrullus, the Latin word for watermelon.Although named and described by gastroenterologists since the late 19th century, it was first isolated from watermelon in 1914 by Japanese researchers Yatarō Koga (古賀彌太郎) and Ryō Ōtake (大嶽了) [3] [4] and further codified by Mitsunori Wada of Tokyo ...
One source recommends an L-citrulline dosage of 2,000 milligrams three times a day, or 1.76 grams of citrulline malate for every 1 gram of citrulline you might take for circulatory health.
Citrulline is not one of the 20 standard amino acids encoded by DNA in the genetic code. Instead, it is the result of a post-translational modification. Citrullination is distinct from the formation of the free amino acid citrulline as part of the urea cycle or as a byproduct of enzymes of the nitric oxide synthase family.
Homocitrulline has been suggested as a confounding antigen for rheumatoid arthritis antibodies targeting citrullinated proteins/peptides. [1] Antibodies binding to homocitrulline-containing sequences have been found in rheumatoid arthritis patients' sera [2] [3] More recently, it has been shown that homocitrulline-containing proteins are present in rheumatoid arthritis (RA) joints. [4]
amitriptyline – tricyclic antidepressant used to treat separation anxiety, excessive grooming dogs and cats; amlodipine – calcium channel blocker used to decrease blood pressure; amoxicillin – antibacterial; apomorphine – emetic (used to induce vomiting) artificial tears – lubricant eye drops used as a tear supplement
Nicotinic acid, [a] or niacin, [b] is an organic compound and a vitamer of vitamin B 3, an essential human nutrient. [ 4 ] [ 5 ] It is produced by plants and animals from the amino acid tryptophan . [ 6 ]
Again, that's a resounding yes. "The skin-strengthening benefits of niacinamide partner well with retinol’s ability to regulate cellular turnover and control oil production," says Hartman.