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  2. Clark's rule - Wikipedia

    en.wikipedia.org/wiki/Clark's_rule

    The procedure is to take the child's weight in pounds, divide by 150 lb, and multiply the fractional result by the adult dose to find the equivalent child dosage.For example, if an adult dose of medication calls for 30 mg and the child weighs 30 lb, divide the weight by 150 (30/150) to obtain 1/5 and multiply 1/5 times 30 mg to get 6 mg.

  3. Volume of distribution - Wikipedia

    en.wikipedia.org/wiki/Volume_of_distribution

    An example for a simple case (mono-compartmental) would be to administer D=8 mg/kg to a human. A human has a blood volume of around V b l o o d = {\displaystyle V_{blood}=} 0.08 L/kg . [ 7 ] This gives a C 0 = {\displaystyle C_{0}=} 100 μg/mL if the drug stays in the blood stream only, and thus its volume of distribution is the same as V b l o ...

  4. Acceptable daily intake - Wikipedia

    en.wikipedia.org/wiki/Acceptable_Daily_Intake

    Acceptable daily intake or ADI is a measure of the amount of a specific substance (originally applied for a food additive, later also for a residue of a veterinary drug or pesticide) in food or drinking water that can be ingested (orally) daily over a lifetime without an appreciable health risk. [1]

  5. Holliday-Segar formula - Wikipedia

    en.wikipedia.org/wiki/Holliday-Segar_formula

    To estimate the daily fluid requirements of a 9-year-old boy who weights 32 kg, 10*100 + 10*50 + 12*20 = 1740 kcal per day. At a 1 kcal / 1 mL conversion, the daily H 2 0 requirements would therefore be 1740 mL.

  6. Broselow tape - Wikipedia

    en.wikipedia.org/wiki/Broselow_tape

    The original Broselow tape was divided into 2.5 kg (5.5 lb) zones for medication doses and eight color zones for equipment selection. Subsequent versions of the tape combined dosing and equipment zones such that the eight color zones contained both dosing and equipment information, thus creating a simple visual system for medication and ...

  7. Defined daily dose - Wikipedia

    en.wikipedia.org/wiki/Defined_Daily_Dose

    For example, atorvastatin once daily at 10mg, 20mg, 40mg and 80mg was prescribed 45%, 36%, 16% and 3% of the time respectively. If one compared cost per unit (daily tablet) then rosuvastatin was instead 24% cheaper than atorvastatin ($1.44 vs $1.90), and if one compares cost per RDD (recorded daily dose) then rosuvastatin was 26% cheaper than ...

  8. Metabolic equivalent of task - Wikipedia

    en.wikipedia.org/wiki/Metabolic_equivalent_of_task

    The metabolic equivalent of task (MET) is the objective measure of the ratio of the rate at which a person expends energy, relative to the mass of that person, while performing some specific physical activity compared to a reference, currently set by convention at an absolute 3.5 mL of oxygen per kg per minute, which is the energy expended when sitting quietly by a reference individual, chosen ...

  9. Specific absorption rate - Wikipedia

    en.wikipedia.org/wiki/Specific_absorption_rate

    Specific energy absorption rate (SAR) averaged over the whole body or over parts of the body, is defined as the rate at which energy is absorbed per unit mass of body tissue and is expressed in watts per kilogram (W/kg). Whole body SAR is a widely accepted measure for relating adverse thermal effects to RF exposure. [9]

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