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Frontotemporal dementia (FTD), also called frontotemporal degeneration disease [1] or frontotemporal neurocognitive disorder, [2] encompasses several types of dementia involving the progressive degeneration of the brain's frontal and temporal lobes. [3] Men and women appear to be equally affected. [1]
Type E presents with neuronal granulofilamentous inclusions and abundant fine grains involving upper (superficial) and lower (deep) cortical layers. This has been associated with behavioral variant of frontotemporal dementia with a rapid clinical course. [5] Two groups independently categorized the various forms of TDP-43 associated disorders.
Frontotemporal dementia, or FTD, is a rare disease that affects parts of the brain controlling behavior and language. These parts of the brain shrink as the disease gets worse. These parts of the ...
As Alzheimer’s disease is the most common form of dementia — affecting an estimated 6.7 million Americans — it’s not surprising that people who experience memory loss may suspect AD.. In ...
The hallmark symptom of LATE is a progressive memory loss that predominantly affects short-term and episodic memory. [1] This impairment is often severe enough to interfere with daily functioning and usually remains the chief neurologic deficit, unlike other types of dementia in which non-memory cognitive domains and behavioral changes might be noted earlier or more prominently. [1]
Alzheimer's disease (AD) is a chronic neurodegenerative disease that results in the loss of neurons and synapses in the cerebral cortex and certain subcortical structures, resulting in gross atrophy of the temporal lobe, parietal lobe, and parts of the frontal cortex and cingulate gyrus. [14]
Consequently, people with vascular dementia tend to perform worse than their Alzheimer's disease counterparts in frontal lobe tasks, such as verbal fluency, and may present with frontal lobe problems: apathy, abulia (lack of will or initiative), problems with attention, orientation, and urinary incontinence.
The study analyzed existing research and data, including a 2022 study that found most biological pathways can be linked to Alzheimer’s disease, and proposed that "stress granules" may be the ...
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