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The Pocock boundary is a method for determining whether to stop a clinical trial prematurely. The typical clinical trial compares two groups of patients. One group are given a placebo or conventional treatment, while the other group of patients are given the treatment that is being tested. The investigators running the clinical trial will wish ...
Anastrozole, sold under the brand name Arimidex among others, is an antiestrogenic medication used in addition to other treatments for breast cancer. [ 7 ] [ 8 ] Specifically it is used for hormone receptor-positive breast cancer. [ 8 ]
The Haybittle–Peto boundary is one such stopping rule, and it states that if an interim analysis shows a probability equal to, or less than 0.001 that a difference as extreme or more between the treatments is found, given that the null hypothesis is true, then the trial should be stopped early. The final analysis is still evaluated at the ...
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Ovarian stimulation with the aromatase inhibitor letrozole has been proposed for ovulation induction in order to treat unexplained female infertility. In a multi-center study funded by the National Institute of Child Health and Development, ovarian stimulation with letrozole resulted in a significantly lower frequency of multiple gestation (i.e., twins or triplets) but also a lower frequency ...
However, according to the U.S. Department of Agriculture's FoodData Central database, as of a few years ago, more than 8,000 branded food products still contained Red Dye No. 3. Common food ...
Other research has found that the rate of VTE is 1 to 5 in 10,000 woman-years in women who are not pregnant or taking a birth control pill, 3 to 9 in 10,000 woman-years in women who are on a birth control pill, 5 to 20 in 10,000 women-years in pregnant women, and 40 to 65 in 10,000 women-years in postpartum women. [104]
"I had 10 years of not paying attention to anything; not accepting any advances, and then I got this script and thought that maybe it was time," the actress said of her new movie 'Back in Action'