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Naproxen/pseudoephedrine, sold under the brand name Aleve-D among others, is a fixed-dose combination medication used for the treatment of nasal congestion and other symptoms of the common cold. [1] It contains naproxen, as the sodium salt, a nonsteroidal anti-inflammatory drug (NSAID); and pseudoephedrine, as the hydrochloride, a nasal ...
The IUPAC names of the two enantiomers are (1S,2S)- respectively (1R,2R)-2-methylamino-1-phenylpropan-1-ol. Synonyms for both are psi -ephedrine and threo -ephedrine. Pseudoephedrine is the INN Tooltip International Nonproprietary Name of the (+)-form, when used as pharmaceutical substance.
The original formula for Actifed contained pseudoephedrine hydrochloride 60 mg as the nasal decongestant and triprolidine hydrochloride 2.5 mg as the antihistamine. . However, in response to widespread laws requiring products containing pseudoephedrine to be kept behind the pharmacy counter, Pfizer changed Actifed's U.S. formula in late 2006 to contain phenylephrine HCl 10 mg as the nasal ...
L-Norpseudoephedrine, or (−)-norpseudoephedrine, is a psychostimulant drug of the amphetamine family. It is one of the four optical isomers of phenylpropanolamine, the other three being cathine ((+)-norpseudoephedrine), (−)-norephedrine, and (+)-norephedrine; as well as one of the two enantiomers of norpseudoephedrine (the other being cathine). [1]
It contains fexofenadine, as the hydrochloride, an antihistamine; and pseudoephedrine, as the hydrochloride, a nasal decongestant. [2] In 2021, it was the 279th most commonly prescribed medication in the United States, with more than 800,000 prescriptions. [5] [6]
It is packaged as white, round, biconvex, uncoated tablets, with each tablet containing 30 mg of pseudoephedrine hydrochloride (PSE), 500 mg of paracetamol (acetaminophen) and 2 mg of chlorpheniramine maleate (CPM) as the active ingredients. [1]
Different ATS also have different toxic dose. Methamphetamine fatality from ATS have been reported after ingestion of a minimal dose of 1.3 mg/kg, while the estimated minimum lethal dose in a non-addicted adult is 200 mg. [14] [26] Generally, children are more likely to develop toxicity and have lower chances of developing tolerance. [14]
The National Precursor Log Exchange (NPLEx) is a real-time electronic logging system which tracks sales of the methamphetamine precursors ephedrine and pseudoephedrine in the United States. The program is operated by the National Association of Drug Diversion Investigators (NADDI), funded by manufacturers of pseudoephedrine medicine, and ...
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