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Kidney stone disease, also known as renal calculus disease, nephrolithiasis or urolithiasis, is a crystallopathy where a solid piece of material (renal calculus) develops in the urinary tract. [2] Renal calculi typically form in the kidney and leave the body in the urine stream. [2] A small calculus may pass without causing symptoms. [2]
Kidney stones are caused by high levels of the minerals calcium, oxalate, and phosphorus in urine. These minerals are normally found in urine and do not cause problems at low levels. However ...
A kidney stone is a hard object, which can be as small as a grain of salt or as big as a golf ball, made from chemicals—calcium oxalate, uric acid, struvite, and cystine—found in our urine ...
AKI - the other main type of kidney disease - can be caused by dehydration, blood loss, urinary tract obstructions such as kidney stones or blood clots, low blood pressure, or heart disease. It ...
The objective of treating IH is preventing nephrolithiasis or the formation of kidney stones. If blood calcium levels are normal, which can rule out hyperparathyroidism , treatment would begin with adopting a diet of ~800 mg of daily calcium, low salt intake, restricted animal protein intake, and increased net fluid intake. [ 8 ]
dialysis usually used in severe hypercalcaemia complicated by kidney failure. Supplemental phosphate should be monitored and added if necessary; phosphate therapy can correct the hypophosphataemia in the face of hypercalcaemia and lower serum calcium, but this can further increase the risk for kidney stones and nephrocalcinosis
Repeated calcium stones associated with medullary sponge kidney may be related to an autosomal dominant mutation of a still unknown gene, however the genes is GDNF seems to be a gene involved in renal morphogenesis. [12] In conjunction with the gene research is another theory of how the disease manifests. This is called the free particle theory.
Treatments depend on the patient, the type of kidney stone and several other factors. These include: Surgical intervention. Some patients may need surgery to remove kidney stones or to help them pass.
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