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Kidney stone disease, also known as renal calculus disease, nephrolithiasis or urolithiasis, is a crystallopathy where a solid piece of material (renal calculus) develops in the urinary tract. [2] Renal calculi typically form in the kidney and leave the body in the urine stream. [2] A small calculus may pass without causing symptoms. [2]
Kidney stones are caused by high levels of the minerals calcium, oxalate, and phosphorus in urine. These minerals are normally found in urine and do not cause problems at low levels.
Some of the oxalate in urine is produced by the body. Calcium and oxalate in the diet play a part but are not the only factors that affect the formation of calcium oxalate stones. Dietary oxalate is an organic ion found in many vegetables, fruits, and nuts. Calcium from bone may also play a role in kidney stone formation.
Kidney stones (nephrolithiasis) are a relatively common and particularly painful disorder. A chronic condition can result in scars to the kidneys. The removal of kidney stones involves ultrasound treatment to break up the stones into smaller pieces, which are then passed through the urinary tract. One common symptom of kidney stones is a sharp ...
In kidney stones, calcium oxalate is the most common mineral type (see nephrolithiasis). Uric acid is the second most common mineral type, but an in vitro study showed uric acid stones and crystals can promote the formation of calcium oxalate stones. [1]
Kidney stones can form through deposits of sodium urate microcrystals. [56] Saturation levels of uric acid in blood may result in one form of kidney stones when the urate crystallizes in the kidney. These uric acid stones are radiolucent, so do not appear on an abdominal plain X-ray. [57]
Small crystals or flakes of it are sometimes found on the surfaces of some cacti, and kidney stones frequently have the same composition. Whewellite was named after William Whewell (1794–1866), an English polymath , naturalist and scientist , professor of moral philosophy at Cambridge and inventor of the system of crystallographic indexing.
Treatments depend on the patient, the type of kidney stone and several other factors. These include: Surgical intervention. Some patients may need surgery to remove kidney stones or to help them pass.
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