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Therefore, the formation of cavities can be a result of hemorrhages which promote cerebral degeneration. [10] In a mouse model, mouse with COL4A1 mutations displayed cerebral hemorrhage , porencephaly, and abnormal development of vascular basement membranes, such as uneven edges, inconsistent shapes, and highly variable thickness. [ 6 ]
Vascular dementia was found to have either comparable or worse survival rates when compared to Alzheimer's disease; [22] another 2014 study found that the prognosis for people with vascular dementia was worse for male and older people. [23] Vascular dementia may be a direct cause of death due to the possibility of a fatal interruption in the ...
People with cranial CSF leaks, the rarer form, have a 10% risk of developing meningitis per year. [55] If cranial leaks last more than seven days, the chances of developing meningitis are significantly higher. [55] Spinal CSF leaks cannot result in meningitis due to the sterile conditions of the leak site. [24]
Childhood dementia is very often diagnosed late, misdiagnosed, or not diagnosed at all. [9] A correct diagnosis happens, on average, 2 years or more after symptoms become apparent. Additionally, children affected by childhood dementia are often misdiagnosed with: Autism [16] [9] [17] Developmental or intellectual delay [16] [9] ADHD [9] Others [9]
SCA is hereditary, progressive, degenerative, and often fatal. There is no known effective treatment or cure. SCA can affect anyone of any age. The disease is caused by either a recessive or dominant gene. In many cases people are not aware that they carry a relevant gene until they have children who begin to show signs of having the disorder. [2]
Treatment is supportive and focused on improving symptoms: Dystonia is a common debilitating symptom and can be managed with oral medications, and sometimes with deep-brain electrical stimulation, therapy support for walking, eating, and manual tasks is essential. Later, in many of the diseases, slowing and stopping of movement (known as ...
None, seizures, dementia, trouble talking, vision problems, one sided weakness [2] Usual onset: Adults [1] Types: WHO Grade 1, 2, or 3 [1] Risk factors: Ionizing radiation, family history [3] Diagnostic method: Medical imaging [2] Differential diagnosis: Haemangiopericytoma, lymphoma, schwannoma, solitary fibrous tumour, metastasis [4] Treatment
Treatment is typically with antibiotics such as clindamycin, meropenem, ampicillin/sulbactam, or moxifloxacin. [1] For those with only chemical pneumonitis, antibiotics are not typically required. [2] Among people hospitalized with pneumonia, about 10% are due to aspiration. [1] It occurs more often in older people, especially those in nursing ...