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Dapoxetine, sold under the brand name Priligy among others, is a selective serotonin reuptake inhibitor (SSRI) used for the treatment of premature ejaculation (PE) in men ages 18 to 64 years old. [ 3 ] [ 4 ] [ 5 ] Dapoxetine works by inhibiting the serotonin transporter , increasing serotonin's action at the postsynaptic cleft, and as a ...
Premature ejaculation (PE) is a male sexual dysfunction that occurs when a male expels semen (and most likely experiences orgasm) soon after beginning sexual activity, and with minimal penile stimulation. [1] It has also been called early ejaculation, rapid ejaculation, rapid climax, premature climax and (historically) ejaculatio praecox.
Numerous chemical substances influence the IELT. Substances such as alcohol and opioids (e.g. heroin, morphine, oxycodone) depress the central nervous system, prolonging the IELT, while selective serotonin reuptake inhibitors (SSRIs) (e.g. dapoxetine) delay ejaculation by blocking a physiological process connected to ejaculatory inevitability, "the male point of no return".
Persistent genital arousal disorder (PGAD), originally called persistent sexual arousal syndrome (PSAS), [1] is spontaneous, persistent, unwanted and uncontrollable genital arousal in the absence of sexual stimulation or sexual desire, [2] [3] and is typically not relieved by orgasm.
Common ejaculatory disorders include: premature ejaculation, retrograde ejaculation, delayed ejaculation, anejaculation, inhibited ejaculation, and anorgasmia. [ 2 ] See also
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Dhat syndrome (Sanskrit: धातु दोष, IAST: Dhātu doṣa) is a condition found in the cultures of South Asia (including Pakistan, India, Bangladesh, Nepal, and Sri Lanka) in which male patients report that they suffer from premature ejaculation or impotence, and believe that they are passing semen in their urine. [1]
One POIS patient with erectile dysfunction and premature ejaculation had much lower severity of symptoms on those occasions when he was able to maintain penile erection long enough to achieve vaginal penetration and ejaculate inside his partner. The patient took tadalafil to treat his erectile dysfunction and premature ejaculation. This ...