Search results
Results from the WOW.Com Content Network
Disruption of typical development may result in the development of both, or neither, duct system, which may produce morphologically intersex individuals. Males: The SRY gene when transcribed and processed produces SRY protein that binds to DNA and directs the development of the gonad into testes. Male development can only occur when the fetal ...
The mesonephric duct, also known as the Wolffian duct, archinephric duct, Leydig's duct or nephric duct, is a paired organ that develops in the early stages of embryonic development in humans and other mammals. It is an important structure that plays a critical role in the formation of male reproductive organs.
It is at the seventh week of gestation that the bodies of non-CAIS individuals with the XY karyotype begin their masculinization: i.e., the Wolffian duct system is promoted and the Müllerian duct system is suppressed (the reverse happens with typically developing females). This process is triggered by androgens produced by the testicles.
Androgen insensitivity syndrome (AIS) is a condition involving the inability to respond to androgens, typically due to androgen receptor dysfunction. [ 1 ] It affects 1 in 20,000 to 64,000 XY ( karyotypically male) births.
Androgens are synthesized in the testes, the ovaries, and the adrenal glands. Androgens increase in both males and females during puberty. [3] The major androgen in males is testosterone. [4] Dihydrotestosterone (DHT) and androstenedione are of equal importance in male development. [4] DHT in utero causes differentiation of the penis, scrotum ...
The testicles are two gonads that produce sperm by meiotic division of germ cells within the seminiferous tubules, [1] and synthesize and secrete androgens that regulate the male reproductive functions. The site of production of androgens is the Leydig cells that are located in the interstitium between seminiferous tubules. [1]
More specifically, androgenetic alopecia is caused by a genetic sensitivity to an androgen called DHT. Your body creates DHT as a byproduct of testosterone, the main androgen hormone in the male body.
The lower part of the mesonephric duct disappears, while the upper part persists as the longitudinal duct of the epoöphoron, called Gartner's duct. There are also developments of other tissues from the mesonephric duct that persist, e.g. the development of the suspensory ligament of the ovary.