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General structure of 25-NB derivatives, where R is usually 2,5-dimethoxy-4-(alkyl or halogen), R 1 is usually H but rarely methyl, and Cyc is usually 2-substituted phenyl but can be other heterocycles. The 25-NB (25x-NBx) series, or NBOMe series, also known as the N-benzylphenethylamines, is a family of serotonergic psychedelics.
25B-NBOH (2C-B-NBOH, NBOH-2C-B) is a derivative of the phenethylamine derived hallucinogen 2C-B which has been sold as a designer drug.It acts as a potent serotonin receptor agonist with similar affinity to the better-known compound 25B-NBOMe at 5-HT 2A and 5-HT 2C receptors with pK i s [clarification needed] values of 8.3 and 9.4, respectively.
25B-NBOMe (NBOMe-2C-B, Cimbi-36, Nova, BOM 2-CB) is a derivative of the phenethylamine psychedelic 2C-B, discovered in 2004 by Ralf Heim at the Free University of Berlin.It acts as a potent full agonist for the 5HT 2A receptor.
A derivative of the substituted phenethylamine 2C-I family, it is the most well-known member of the 25-NB family. It was discovered in 2003 by chemist Ralf Heim at the Free University of Berlin, who published his findings in his PhD dissertation. [5] The compound was subsequently investigated by a team at Purdue University led by David Nichols. [6]
25N-NBPh (NBPh-2C-N) is a phenethylamine derivative from the 25-NB class, which acts as a potent agonist at the 5-HT 2A receptor with weaker activity at 5-HT 2B and 5-HT 2C. 25N-NBPh is a biased agonist, producing robust activation of 5-HT 2A coupled signalling pathways mediated by beta arrestin 2, but with only slight activation of pathways mediated via G q.
The Riksdag added 25B-NBF to Narcotic Drugs Punishments Act under swedish schedule I ("substances, plant materials and fungi which normally do not have medical use") as of January 26, 2016, published by Medical Products Agency (MPA) in regulation HSLF-FS 2015:35 listed as 25B-NBF, and 2-(4-bromo-2,5-dimetoxifenyl)-N-(2-fluorobensyl)etanamin.
At the collegiate level, Milroe lived for four seasons at Alabama, including the final two as a starter. Milroe’s air success in 2023 exceeded his most recent campaign, his touchdown-to ...
25C-NBOMe (NBOMe-2C-C, 2C-C-NBOMe, Cimbi-82) is a psychedelic drug and derivative of the psychedelic phenethylamine 2C-C. 25C-NBOMe appeared on online vendor sites in 2010 but was not reported in the literature until 2011. [3]