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Blastocystis hominis is a single-celled eukaryotic organism that inhabits the gastrointestinal tract of humans and various animals. [1] This stramenopile exhibits significant genetic diversity and has become an organism of increasing scientific interest due to its widespread distribution and controversial role in human health. [ 2 ]
Researchers have published conflicting reports concerning whether Blastocystis causes symptoms in humans, with one of the earliest reports in 1916. [2] The incidence of reports associated with symptoms began to increase in 1984, [3] with physicians from Saudi Arabia reporting symptoms in humans [4] and US physicians reporting symptoms in individuals with travel to less developed countries. [5]
In the early 2000s, Egyptian physicians identified 84 patients with diarrhea and enteritis apparently caused by Blastocystis hominis. After three days of nitazoxanide treatment, symptoms cleared and no fecal organisms were detectable in 36 (86%) of 42 treated patients and in 16 (38%) of 42 people who received placebo (P < .0001).
The lethal dose for 50% of dogs is 100 – 200 mg per kilogram (kg) of body weight, yet some dogs will exhibit signs of toxicosis after ingesting as little as 20 mg per kg. [38] In case of accidental intake of chocolate, especially involving a smaller dog, contact a veterinarian or animal poison control immediately; it is commonly recommended ...
Acetaminophen (paracetamol, Tylenol) can cause liver damage in dogs. The toxic dose is 150 mg/kg. [174] Ibuprofen * can cause gastrointestinal irritation, stomach ulcers, and kidney damage in dogs. [175] Naproxen (Aleve)* has a long half-life in dogs and can cause gastrointestinal irritation, anemia, melena (digested blood in feces), and vomiting.
Blastocystis is a single-celled protozoan which infects the large intestine. Physicians report that patients with infection show symptoms of abdominal pain, constipation, and diarrhea. [54] [55] [56] One study found that 43% of IBS patients were infected with Blastocystis versus 7% of controls. [49]
Domestic dogs in Belgium showed a mean prevalence of T. canis of 4.4%, those from larger kennels of up to 31%. [6] In domestic dogs in Serbia, T. canis was detectable in 30% of the animals, [7] in herding and hunting dogs in Greece in 12.8% and T. leonina in 0.7% of animals. [8]
Dog with atopic dermatitis, with signs around the eye created by rubbing. Atopy is a hereditary [3] and chronic (lifelong) allergic skin disease. Signs usually begin between 6 months and 3 years of age, with some breeds of dog, such as the golden retriever, showing signs at an earlier age.
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