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Synthetic retinoids are utilized in cosmetic formulations, clinical dermatology, and the treatment of some forms of cancer. [ 1 ] Retinoids have many important functions throughout the body, including in vision, [ 2 ] regulation of skin proliferation and differentiation, growth of bone tissue, immune function, [ 3 ] and male fertility.
Retinyl palmitate is also a constituent of some topically applied skin care products. After its absorption into the skin, retinyl palmitate is converted to retinol, and ultimately to retinoic acid (the active form of vitamin A present in Retin-A), though neither its skin absorption [ 6 ] nor its conversion [ 7 ] is very effective.
Topical tretinoin is for use only on the skin and should not be applied to eyes or mucosal tissues. Common side effects include skin irritation, redness, swelling, and blistering. [ 6 ] If irritation is a problem, a decrease in the frequency of application to every other or every third night can be considered, and the frequency of application ...
Retinol, also called vitamin A 1, is a fat-soluble vitamin in the vitamin A family that is found in food and used as a dietary supplement. [3] Retinol or other forms of vitamin A are needed for vision, cellular development, maintenance of skin and mucous membranes , immune function and reproductive development. [ 3 ]
Vitamin A toxicity also referred to as hypervitaminosis A, occurs when there is too much vitamin A accumulating in the body. Symptoms may include nervous system effects, liver abnormalities, fatigue, muscle weakness, bone and skin changes, and others. The adverse effects of both acute and chronic toxicity are reversed after consumption of high ...
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The view of the medical community is that there is no evidence for the efficacy of Orthomolecular medicine as a treatment for cancer, [6] and that high vitamin doses may – on the contrary – increase overall mortality. [73] Nutritional treatments are not generally accepted as being helpful for psychological health. [74]
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