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  2. List of Guidances for Statistics in Regulatory Affairs

    en.wikipedia.org/wiki/List_of_Guidances_for...

    FDA: Good Review Practice: Clinical Review of Investigational New Drug Applications. [2] This good review practice (GRP) document was prepared to assist FDA clinical review staff in reviewing clinical submissions to an investigational new drug application (IND) from the pre-IND phase to the time of the pre-new drug application/biologics license ...

  3. Investigational New Drug - Wikipedia

    en.wikipedia.org/wiki/Investigational_new_drug

    The United States Food and Drug Administration's Investigational New Drug (IND) program is the means by which a pharmaceutical company obtains permission to start human clinical trials and to ship an experimental drug across state lines (usually to clinical investigators) before a marketing application for the drug has been approved.

  4. New Drug Application - Wikipedia

    en.wikipedia.org/wiki/New_Drug_Application

    To legally test the drug on human subjects in the United States, the maker must first obtain an Investigational New Drug (IND) designation from FDA. [5] This application is based on nonclinical data, typically from a combination of in vivo and in vitro laboratory safety studies, that shows the drug is safe enough to test in humans. [5]

  5. CFR - Code of Federal Regulations Title 21

    highline.huffingtonpost.com/miracleindustry/...

    [revised as of april 1, 2015] [cite: 21cfr314.50] title 21­­food and drugs chapter i­­food and drug administration department of health and human services subchapter d­­drugs for human use part 314 ­­ applications for fda approval to market a new drug subpart b­­applications

  6. Electronic common technical document - Wikipedia

    en.wikipedia.org/wiki/Electronic_Common...

    The electronic common technical document (eCTD) is an interface and international specification for the pharmaceutical industry to agency transfer of regulatory information. The specification is based on the Common Technical Document (CTD) format and was developed by the International Council for Harmonisation (ICH) Multidisciplinary Group 2 ...

  7. Standard for Exchange of Non-clinical Data - Wikipedia

    en.wikipedia.org/wiki/Standard_for_Exchange_of...

    This was soon followed by the FDA's statement of preference for SEND datasets. In December 2014, the FDA CDER and CBER divisions released guidance for industry enforcing the usage of SEND as part of Investigational New Drug (IND) and Biologic License Application (BLA) submission to the US Food and Drug Administration. All studies started after ...

  8. Fast track (FDA) - Wikipedia

    en.wikipedia.org/wiki/Fast_track_(FDA)

    Fast track is a designation by the United States Food and Drug Administration (FDA) of an investigational drug for expedited review to facilitate development of drugs that treat a serious or life-threatening condition and fill an unmet medical need. Fast track designation must be requested by the drug company.

  9. Drug development - Wikipedia

    en.wikipedia.org/wiki/Drug_development

    Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery.It includes preclinical research on microorganisms and animals, filing for regulatory status, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may ...

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