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Basophilic stippling, also known as punctate basophilia, is the presence of numerous basophilic granules that are dispersed through the cytoplasm of erythrocytes in a peripheral blood smear. They can be demonstrated to be RNA .
A cell containing Pappenheimer bodies is a siderocyte. Reticulocytes often contain Pappenheimer bodies. They are mostly observed in diseases such as myelodysplastic syndrome (MDS), sideroblastic anemia, hemolytic anemia, lead poisoning and sickle cell disease. They can interfere with platelet counts when the analysis is performed by electro ...
Lead poisoning, also known as ... However, basophilic stippling is also seen in unrelated conditions, such as megaloblastic anemia caused by vitamin B12 (colbalamin) ...
With lead poisoning, see coarse basophilic stippling of red blood cells on peripheral blood smear; Specific test: Prussian blue stain of RBC in marrow shows ringed sideroblasts. Prussian blue staining involves a non-enzymatic reaction of ferrous iron with ferrocyanide forming ferric-ferrocyanide, which is blue in color.
That would seem to back up a study, published in 2022 in the journal Science, that found “unexpectedly high frequencies of lead poisoning of eagles” when it looked at 1,210 bald and golden ...
A Monroe County resident under the age of six has a blood lead level of greater than 3.5 micrograms per deciliter but less than 10 micrograms per deciliter, Dr. Michael Mendoza, Monroe County's ...
Basophilic stippling is one morphologic finding of thalassemia which does not appear in iron deficiency or anemia of chronic disease. The patient should be in an ethnically at-risk group and the diagnosis is not confirmed without a confirmatory method such as hemoglobin HPLC, H body staining, molecular testing or another reliable method.
The number of children with lead poisoning potentially linked to tainted pouches of cinnamon apple puree and cinnamon applesauce has increased to 64, the Food and Drug Administration reported ...