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  2. Evolutionary models of human drug use - Wikipedia

    en.wikipedia.org/wiki/Evolutionary_models_of...

    The dominant paradigm of drug abuse focuses on human neurobiology and suggests that drug use is the result of reward-related behavior and that drug addiction is a consequence of drug interference with natural reward systems. [3]

  3. Thecodont dentition - Wikipedia

    en.wikipedia.org/wiki/Thecodont_dentition

    Thecodont dentition is a morphological arrangement in which the base of the tooth is completely enclosed in a deep socket of bone, as seen in crocodilians, dinosaurs and mammals, and opposed to acrodont and pleurodont dentition seen in squamate reptiles. [1] Notably, this appears to be the ancestral tooth condition in Amniota. [2]

  4. Thecodontia - Wikipedia

    en.wikipedia.org/wiki/Thecodontia

    Thecodontia (meaning 'socket-teeth'), now considered an obsolete taxonomic grouping, was formerly used to describe a diverse "order" of early archosaurian reptiles that first appeared in the latest Permian period and flourished until the end of the Triassic period. All of them were built somewhat like crocodiles but with shorter skulls, more ...

  5. Disease model of addiction - Wikipedia

    en.wikipedia.org/wiki/Disease_model_of_addiction

    The common biomolecular mechanisms underlying addiction – CREB and ΔFosB – were reviewed by Eric J. Nestler in a 2013 review. [3] Genetics and mental disorders may precipitate the severity of a drug addiction. It is estimated that 50% of healthy individuals developing an addiction can trace the cause to genetic factors. [4]

  6. Substance-related disorder - Wikipedia

    en.wikipedia.org/wiki/Substance-related_disorder

    Substance use, also known as drug use, is a patterned use of a substance (drug) in which the user consumes the substance in amounts or with methods which are harmful to themselves or others. The drugs used are often associated with levels of substance intoxication that alter judgment, perception, attention and physical control, not related with ...

  7. Addiction-related structural neuroplasticity - Wikipedia

    en.wikipedia.org/wiki/Addiction-related...

    In drug addiction, the drug-seeking behaviors become reinforced by the rush of dopamine that follows the administration of a drug of abuse. The effects of drugs of abuse on the ventral tegmental area (VTA) and the nucleus accumbens (NAc) have been studied extensively. [16] Drugs of abuse change the complexity of dendritic branching as well as ...

  8. Substance use disorder - Wikipedia

    en.wikipedia.org/wiki/Substance_use_disorder

    "Substance use pertains to using select substances such as alcohol, tobacco, illicit drugs, etc. that can cause dependence or harmful side effects."On the other hand, substance abuse is the use of drugs such as prescriptions, over-the-counter medications, or alcohol for purposes other than what they are intended for or using them in excessive ...

  9. Addiction Biology - Wikipedia

    en.wikipedia.org/wiki/Addiction_Biology

    Addiction Biology is a quarterly peer-reviewed scientific journal covering research on substance abuse. It is one of two journals published on behalf of the Society for the Study of Addiction to Alcohol and other Drugs. The major focus of Addiction Biology is on neuroscience contributions from animal experimentation and clinical point of views.

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