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  2. DNA replication - Wikipedia

    en.wikipedia.org/wiki/DNA_replication

    In contrast, DNA Pol I is the enzyme responsible for replacing RNA primers with DNA. DNA Pol I has a 5′ to 3′ exonuclease activity in addition to its polymerase activity, and uses its exonuclease activity to degrade the RNA primers ahead of it as it extends the DNA strand behind it, in a process called nick translation. Pol I is much less ...

  3. Gene - Wikipedia

    en.wikipedia.org/wiki/Gene

    Selected portions of the DNA nucleotide sequence are copied into a corresponding RNA nucleotide sequence, which either encodes a protein (if it is an mRNA) or forms a 'structural' RNA, such as a transfer RNA (tRNA) or ribosomal RNA (rRNA) molecule. Each region of the DNA helix that produces a functional RNA molecule constitutes a gene. [15]

  4. Central dogma of molecular biology - Wikipedia

    en.wikipedia.org/wiki/Central_dogma_of_molecular...

    A second version of the central dogma is popular but incorrect. This is the simplistic DNARNA → protein pathway published by James Watson in the first edition of The Molecular Biology of the Gene (1965). Watson's version differs from Crick's because Watson describes a two-step (DNARNA and RNA → protein) process as the central ...

  5. RNA - Wikipedia

    en.wikipedia.org/wiki/RNA

    It has become widely accepted in science [1] that early in the history of life on Earth, prior to the evolution of DNA and possibly of protein-based enzymes as well, an "RNA world" existed in which RNA served as both living organisms' storage method for genetic information—a role fulfilled today by DNA, except in the case of RNA viruses—and ...

  6. DNA - Wikipedia

    en.wikipedia.org/wiki/DNA

    RNA-dependent DNA polymerases are a specialized class of polymerases that copy the sequence of an RNA strand into DNA. They include reverse transcriptase , which is a viral enzyme involved in the infection of cells by retroviruses , and telomerase , which is required for the replication of telomeres.

  7. Transcription (biology) - Wikipedia

    en.wikipedia.org/wiki/Transcription_(biology)

    Some segments of DNA are transcribed into RNA molecules that can encode proteins, called messenger RNA (mRNA). Other segments of DNA are transcribed into RNA molecules called non-coding RNAs (ncRNAs). Both DNA and RNA are nucleic acids, which use base pairs of nucleotides as a complementary language. During transcription, a DNA sequence is read ...

  8. Eukaryotic transcription - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_transcription

    Double stranded DNA that enters from the front of the enzyme is unzipped to avail the template strand for RNA synthesis. For every DNA base pair separated by the advancing polymerase, one hybrid RNA:DNA base pair is immediately formed. DNA strands and nascent RNA chain exit from separate channels; the two DNA strands reunite at the trailing end ...

  9. Self-replication - Wikipedia

    en.wikipedia.org/wiki/Self-replication

    Self-replication is a fundamental feature of life. It was proposed that self-replication emerged in the evolution of life when a molecule similar to a double-stranded polynucleotide (possibly like RNA) dissociated into single-stranded polynucleotides and each of these acted as a template for synthesis of a complementary strand producing two double stranded copies. [4]

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