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An agonist is a molecule that activates certain receptors (i.e., specific cellular proteins) in a cell to produce a specific pharmacological response, causing the cell to modify its activity—while an inverse agonist targets the same receptors as those of a given agonist, but causes a response opposite to that caused by the agonist.
The biochemistry of Alzheimer's disease, the most common cause of dementia, is not yet very well understood. Alzheimer's disease (AD) has been identified as a proteopathy: a protein misfolding disease due to the accumulation of abnormally folded amyloid beta (Aβ) protein in the brain. [1]
In fact, dementia has become the leading cause of death for women in England. [305] There, as with all mental disorders, people with dementia could potentially be a danger to themselves or others, they can be detained under the Mental Health Act 1983 for assessment, care and treatment. This is a last resort, and is usually avoided by people ...
After adjusting for sociodemographic and lifestyle factors, family history of dementia, baseline cognitive function and medications that affect cognition, the researchers analyzed whether there ...
A link between these types of drugs and cognitive impairment isn't a totally new discovery, but for the first time, researchers used brain imaging techniques to determine the physical changes ...
People who maintain or start physical activity of any intensity after receiving a dementia diagnosis may be at a decreased risk for all-cause mortality, a new study suggests.
Failure to thrive [8] and aspiration pneumonia, a complication of dysphagia (difficulty swallowing) that results from dysautonomia, commonly cause death among people with the Lewy body dementias. [80] Cardiovascular disease and sepsis are also common causes of death. [163]
Repeated use of a certain class of drugs for heartburn was linked with a higher risk for dementia among patients in Germany, researchers say. Gastric reflux drugs may be tied to dementia risk Skip ...
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