Search results
Results from the WOW.Com Content Network
In genetics, a transcription terminator is a section of nucleic acid sequence that marks the end of a gene or operon in genomic DNA during transcription.This sequence mediates transcriptional termination by providing signals in the newly synthesized transcript RNA that trigger processes which release the transcript RNA from the transcriptional complex.
Once RNA polymerase reaches the termination signal, transcription is terminated. [1] In bacteria, there are two main types of termination signals: intrinsic and factor-dependent terminators. [1] In the context of translation, a termination signal is the stop codon on the mRNA that elicits the release of the growing peptide from the ribosome. [2]
[2] [3] The mRNA sequence is determined by the sequence of genomic DNA. [4] In this context, the standard genetic code is referred to as translation table 1. [3] It can also be represented in a DNA codon table. The DNA codons in such tables occur on the sense DNA strand and are arranged in a 5 ′-to-3 ′ direction.
Stop codon (red dot) of the human mitochondrial DNA MT-ATP8 gene, and start codon (blue circle) of the MT-ATP6 gene. For each nucleotide triplet (square brackets), the corresponding amino acid is given (one-letter code), either in the +1 reading frame for MT-ATP8 (in red) or in the +3 frame for MT-ATP6 (in blue).
The last stage of transcription is termination, which leads to the dissociation of the complete transcript and the release of RNA polymerase from the template DNA.The process differs for each of the three RNA polymerases. [35] The mechanism of termination is the least understood of the three transcription stages.
Reading frames in the DNA sequence of a region of the human mitochondrial genome coding for the genes MT-ATP8 and MT-ATP6 (in black: positions 8,525 to 8,580 in the sequence accession NC_012920 [31]). There are three possible reading frames in the 5' → 3' forward direction, starting on the first (+1), second (+2) and third position (+3).
They are required for the termination of DNA replication and function by binding to DNA replication terminator sequences, thus preventing the passage of replication forks. [1] The termination efficiency is affected by the affinity of a particular protein for the terminator sequence .
This table is found in both DNA Codon Table and Genetic Code (And probably a few other places), so I'm pulling it out so it can be common. By default it's the DNA code (using the letter T for Thymine); use template parameter "T=U" to make it the RNA code (using U for Uracil). See also Template:Inverse codon table