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DNA nanotechnology, specifically, is an example of bottom-up molecular self-assembly, in which molecular components spontaneously organize into stable structures; the particular form of these structures is induced by the physical and chemical properties of the components selected by the designers. [19]
Nucleic acid design is used in DNA nanotechnology to design strands which will self-assemble into a desired target structure. These include examples such as DNA machines, periodic two- and three-dimensional lattices, polyhedra, and DNA origami. [2]
The physical and mathematical analysis of X-ray [16] [17] and spectroscopic data for paracrystalline B-DNA is thus far more complex than that of crystalline, A-DNA X-ray diffraction patterns. The paracrystal model is also important for DNA technological applications such as DNA nanotechnology. Novel methods that combine X-ray diffraction of DNA ...
Single-stranded and double-stranded versions of these materials have been created using, for example, DNA, LNA, and RNA. One- and two-dimensional forms of nucleic acids (e.g., single strands, linear duplexes, and plasmids ) (Fig. 1) are important biological machinery for the storage and transmission of genetic information .
The method of DNA origami was developed by Paul Rothemund at the California Institute of Technology. [6] In contrast to common top-down fabrication methods such as 3D printing or lithography which involve depositing or removing material through a tool, DNA Nanotechnology, as well as DNA Origami as a subset, is a bottom-up fabrication method.
Every BioBrick part is a DNA sequence which is carried by a circular plasmid, which acts as a vector. [12] The vector acts as a transport system to carry the BioBrick parts. The first approach towards a BioBrick standard was the introduction of standard sequences, the prefix and suffix sequences, which flank the 5 ′ and 3 ′ ends of the DNA ...
For example, DNA nanotechnology or cellular engineering would be classified as bionanotechnology because they involve working with biomolecules on the nanoscale. Conversely, many new medical technologies involving nanoparticles as delivery systems or as sensors would be examples of nanobiotechnology since they involve using nanotechnology to ...
A nanostructure is a structure of intermediate size between microscopic and molecular structures. Nanostructural detail is microstructure at nanoscale. In describing nanostructures, it is necessary to differentiate between the number of dimensions in the volume of an object which are on the nanoscale.