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Most people with schizophrenia live independently with community support. [1] In people with a first episode of psychosis a good long-term outcome occurs in 42% of cases, an intermediate outcome in 35% of cases, and a poor outcome in 27% of cases. [7] Outcome for schizophrenia appear better in the developing than the developed world. [8]
Myasthenia gravis affects 50 to 200 people per million. [3] [4] It is newly diagnosed in 3 to 30 people per million each year. [13] Diagnosis has become more common due to increased awareness. [13] Myasthenia gravis most commonly occurs in women under the age of 40 and in men over the age of 60. [1] [5] [14] It is uncommon in children. [1]
A new first-in-class antipsychotic that targets multiple neurotransmitter systems called lumateperone (ITI-007), was trialed and approved by the FDA in December 2019 for the treatment of schizophrenia in adults. [24] [26] [27] Lumateperone is a small molecule agent that shows improved safety, and tolerance.
In some conditions, such as myasthenia gravis, muscle strength is normal when resting, but true weakness occurs after the muscle has been subjected to exercise. This is also true for some cases of chronic fatigue syndrome, where objective post-exertion muscle weakness with delayed recovery time has been measured and is a feature of some of the ...
The time between the onset of psychotic symptoms to being given treatment – the duration of untreated psychosis (DUP) – is associated with a poorer outcome in both the short term and the long term. [187] Voluntary or involuntary admission to hospital may be imposed by doctors and courts who deem a person to be having a severe episode.
Schizophrenia is diagnosed 1.4 times more frequently in males than females, and typically appears earlier in men [7] —the peak ages of onset schizophrenia are 20–28 years for males and 26–32 years for females. [10] Early Onset schizophrenia in childhood, before the age of 13 can sometimes occur.
The outcomes paradox (otherwise known as the "better prognosis hypothesis") is the observation that patients with schizophrenia in developing countries benefit much more from therapy than those in developed countries. This is surprising because the reverse holds for most diseases: "the richer and more developed the country, the better the ...
In psychiatry, catastrophic schizophrenia or schizocaria is an outdated term for a rare, [1] [2] acute form of schizophrenia leading to chronic psychosis [3] and deterioration of the personality. [1] Catastrophic schizophrenia was thought to be the most severe subtype of schizophrenia, as it had "an acute onset and rapid decline into a chronic ...
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