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Metals in medicine are used in organic systems for diagnostic and treatment purposes. [1] Inorganic elements are also essential for organic life as cofactors in enzymes called metalloproteins . When metals are under or over-abundant in the body, equilibrium must be returned to its natural state via interventional and natural methods.
Platinum-based antineoplastic drugs (informally called platins) are chemotherapeutic agents used to treat cancer. Their active moieties are coordination complexes of platinum . These drugs are used to treat almost half of people receiving chemotherapy for cancer.
Platinum is the most promising candidate among pure metals for application in DMFCs. Platinum has the highest activity toward the dissociative adsorption of methanol. However, pure Pt surfaces are poisoned by carbon monoxide, a byproduct of methanol oxidation. Researchers have focused on dispersing nanostructured catalysts on high surface area ...
Platinum is a chemical element; it has symbol Pt and atomic number 78. It is a dense, malleable, ductile, highly unreactive, precious, silverish-white transition metal. Its name originates from Spanish platina, a diminutive of plata "silver". [7] [8] Platinum is a member of the platinum group of elements and group 10 of the periodic table of ...
It plays an important role in maintenance of the cell membrane potential and the electrochemical gradient in the body via the sodium-potassium pump and sodium-glucose transport proteins. Sodium also serves a purpose in the nervous system and cell communication as they flood into axons during an action potential to preserve the strength of the ...
Cisplatin is administered intravenously as short-term infusion in normal saline for treatment of solid and haematological malignancies. It is used to treat various types of cancers, including sarcomas, some carcinomas (e.g., small cell lung cancer, squamous cell carcinoma of the head and neck and ovarian cancer), lymphomas, bladder cancer, cervical cancer, [9] and germ cell tumors.
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At the biological interface, medicinal chemistry combines to form a set of highly interdisciplinary sciences, setting its organic, physical, and computational emphases alongside biological areas such as biochemistry, molecular biology, pharmacognosy and pharmacology, toxicology and veterinary and human medicine; these, with project management ...