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Purpura, arthritis, and abdominal pain are known as the "classic triad" of Henoch–Schönlein purpura. [5] Purpura occur in all cases, joint pains and arthritis in 80%, and abdominal pain in 62%. Some include gastrointestinal hemorrhage as a fourth criterion; this occurs in 33% of cases, sometimes, but not necessarily always, due to ...
Henoch–Schönlein purpura (HSP, German: Purpura Schönlein-Henoch, also known as "anaphylactoid purpura", "purpura rheumatica", and "Schönlein–Henoch purpura) Blasius Schönlein, Abbot (1585 - 1595) of the Cloister of St. Georgen im Schwarzwald; Herrmann Schönlein (1833–1908), German publisher
Schönlein described purpura rheumatica (Schönlein's disease) an allergic non-thrombopenic purpura rash that became known as Henoch–Schönlein purpura, though now known as IgA vasculitis. [3] [4] He also discovered the parasitic cause of ringworm or favus (Trichophyton schönleinii). [5]
Cryofibrinogenemia refers to a condition classified as a fibrinogen disorder in which a person's blood plasma is allowed to cool substantially (i.e. from its normal temperature of 37 °C to the near-freezing temperature of 4 °C), causing the (reversible) precipitation of a complex containing fibrinogen, fibrin, fibronectin, and, occasionally, small amounts of fibrin split products, albumin ...
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Henoch–Schönlein purpura (HSP) - Often considered a systemic form of IgA nephropathy, Henoch–Schönlein purpura (HSP) is a systemic small-vessel vasculitis that is characterized by deposition of IgA antibody immune complexes in different key areas throughout the body.
Eduard Heinrich Henoch (June 16, 1820 Berlin – August 26, 1910) was a German physician. He taught at the Berlin University (1868–1894). Henoch was of Jewish descent, and was the nephew of Moritz Heinrich Romberg .
Immune complex glomerulonephritis, as seen in Henoch-Schönlein purpura; this is an example of IgA involvement in a nephropathy. The reaction can take hours, days, or even weeks to develop, depending on whether or not there is immunological memory of the precipitating antigen. Typically, clinical features emerge a week following initial antigen ...