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Choluria (or bilirubinuria) is a symptom defining an abnormal darkness of the urine, mainly due to a high level of conjugated bilirubin. [1] [2] Choluria is a common symptom of liver diseases, such as hepatitis and cirrhosis. It can be described as dark or brown urine, often referred to as the color of Coca-Cola.
Worsening cirrhosis can cause a build-up of fluid in different parts of the body such as the legs and abdomen . [13] Other signs of advancing disease include itchy skin, bruising easily, dark urine, and yellowing of the skin. [13]
However, infants with biliary atresia develop progressive conjugated jaundice, pale white stools, and dark urine. Some infants fail to thrive as there will be a degree of fat and fat-soluble vitamin malabsorption (e.g. Vitamin K). This may cause a bleeding tendency. Eventually, and usually after 2 months, cirrhosis with portal hypertension will ...
Chronic infections (like hepatitis or HIV) can also cause excess protein in your urine, says Dr. Liss. Some infections can directly attack the kidney filters while others cause inflammation that ...
What does your urine odor say? Urine typically has a mild odor, but strong or unusual smells can indicate a problem. A strong ammonia scent could suggest dehydration.
Abdominal pain could indicate biliary tract obstruction and cirrhosis. [4] Urinalysis serves as a first-line diagnostic tool. Conjugated bilirubin, being water-soluble, is excreted through urine. Hence, dark urine tested bilirubin positive signifies conjugated hyperbilirubinemia. [3] A peripheral blood smear showing signs of haemolysis.
Clinically, jaundice or dark urine present in approximately one-third of the cases, and most of the symptoms are related to anemia. [5] Other less commonly observed causes of hemolysis include: Hemolysis secondary to drug toxicity [15] Thalassemia minor [16] Congenital dyserythropoietic anemia [17]
However, according to the Mayo Clinic, some liver and kidney disorders, as well as some urinary tract infections, can turn urine dark brown and warrant a doctor’s visit. If your urine is cloudy…
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