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In light of recent evidence, olanzapine (Zyprexa) has been FDA approved as an effective monotherapy for the maintenance of bipolar disorder. [22] A head-to-head randomized control trial in 2005 has also shown olanzapine monotherapy to be just as effective and safe as lithium in prophylaxis. [23]
FDA approved for bipolar disorder maintenance therapy, not for acute mood problems like depression or mania/hypomania. [10] The usual target dose is 100–200 mg daily, titrated to by 25 mg increments every 2 weeks. [11] Lamotrigine can cause Stevens–Johnson syndrome, a very rare but potentially fatal skin condition. [10] Carbamazepine
Asenapine has been approved by the FDA for the acute treatment of adults with schizophrenia and acute treatment of manic or mixed episodes associated with bipolar I disorder with or without psychotic features in adults. [12] In Australia asenapine's approved (and also listed on the PBS) indications include the following: [14] Schizophrenia
This includes medication, psychotherapy, and lifestyle strategies. Bipolar disorder is a serious mental health condition affecting 2.8 percent of adults in the United States. It involves episodes ...
It is approved by the FDA for the following indications: schizophrenia. acute treatment of manic or mixed episodes associated with bipolar I disorder and maintenance treatment of bipolar I disorder. adjunct to lithium or valproate in the treatment of manic or mixed episodes associated with bipolar I disorder.
Lamotrigine is approved in the US for maintenance treatment of bipolar I disorder and bipolar II disorder. [24] While the anticonvulsants carbamazepine and valproate are predominantly antimanics , lamotrigine has demonstrated efficacy only in preventing or reducing the risk of recurrent depressive episodes of bipolar disorder.
In 2013, it was approved in Canada and by the U.S. Food and Drug Administration (FDA) to treat bipolar depression, either as monotherapy or adjunctively with lithium or valproate. [ 15 ] [ 16 ] It has no effect on manic symptoms and is more potent for treating major depressive disorder or depressive episodes associated with bipolar disorder.
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.