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The Dietary Inflammatory Index (DII) is a numerical score that assesses a diet for its effect on several biomarkers linked to inflammation. Its theoretical bounds are −8.87 to +7.98, and it is oriented such that negative scores are more anti-inflammatory and more positive scores are pro-inflammatory .
Chicken and white beans pack in the protein. Any white beans, such as cannellini, garbanzo or navy beans, work well here. To keep the phyllo dough from drying out as you build the casserole, keep ...
Breakfast (361 calories) 1 cup low-fat plain strained Greek-style yogurt. ¼ cup sliced almonds. ½ cup cherries. 1 serving No-Added-Sugar Chia Seed Jam. A.M. Snack (193 calories)
C-reactive protein (CRP) is an annular (ring-shaped) pentameric protein found in blood plasma, whose circulating concentrations rise in response to inflammation. It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages and T cells .
The terms acute-phase protein and acute-phase reactant (APR) are often used synonymously, although some APRs are (strictly speaking) polypeptides rather than proteins. In response to injury , local inflammatory cells ( neutrophil granulocytes and macrophages ) secrete a number of cytokines into the bloodstream, most notable of which are the ...
Inflammaging is thought to be caused by a loss of control over systemic inflammation resulting in chronic overstimulation of the innate immune system. Inflammaging is a significant risk factor in mortality and morbidity in aged individuals. [2] [3] [4] Inflammation is essential to protect against viral and bacterial infection, as well as ...
Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. [5] In addition, osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine.
A balance between proinflammatory and anti-inflammatory cytokines is necessary to maintain health. Aging and exercise also play a role in the amount of inflammation from the release of proinflammatory cytokines. Therapies to treat inflammatory diseases include monoclonal antibodies that either neutralize inflammatory cytokines or their receptors.