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Simvastatin, sold under the brand name Zocor among others, is a statin, a type of lipid-lowering medication. [4] It is used along with exercise, diet, and weight loss to decrease elevated lipid levels. [4] It is also used to decrease the risk of heart problems in those at high risk. [4] It is taken by mouth. [4]
With median follow-up of 6 years, simvastatin+ezetimibe was found to reduce the primary outcome of CV mortality, major CV event, or nonfatal stroke (34.7% vs. 32.7%; P=0.016; NNT 50 per 7 years or NNT 350 per 1 year ). There was no reduction in all-cause or CV mortality with simvastatin+ezetimibe, though there was a reduction in MI and stroke. [6]
Zokors are Asiatic burrowing rodents resembling mole-rats.They include two genera: Myospalax and Eospalax.Zokors are native to much of China, Kazakhstan, and Siberian Russia.
The bites may be pimple-like, blister-like or similar to hives. They typically appear in specific areas on the lower body where tight clothes meet skin, like at the cuffs of your socks or the ...
Simvastatin: No tumorigenic effect was seen in a 72-week carcinogenicity study using mice at the low dose levels. However, at the higher dose levels (eight and 16 times the human dose equivalent), liver carcinomas and adenomas, lung adenomas, and adenomas of the Harderian gland occurred. No mutagenic effects were seen in assays.
Niacin/simvastatin (trade name Simcor, by Abbott) is a combination drug consisting of an extended release form of the lipid-lowering drug niacin and the statin drug simvastatin. [1] It is used for the treatment of dyslipidemia .
10599 28253 Ensembl ENSG00000134538 ENSMUSG00000030236 UniProt Q9Y6L6 Q9JJL3 RefSeq (mRNA) NM_006446 NM_020495 NM_178235 RefSeq (protein) NP_006437 NP_065241 Location (UCSC) Chr 12: 21.13 – 21.24 Mb Chr 6: 141.58 – 141.63 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Solute carrier organic anion transporter family member 1B1 is a protein that in humans is encoded by the SLCO1B1 ...
ATC code C10 Lipid modifying agents is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
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