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A glass of red wine. The health effects of wine are mainly determined by its active ingredient – alcohol. [1] [2] Preliminary studies found that drinking small quantities of wine (up to one standard drink per day for women and one to two drinks per day for men), particularly of red wine, may be associated with a decreased risk of cardiovascular diseases, cognitive decline, stroke, diabetes ...
“When alcohol is metabolized, it produces acetaldehyde, a toxic compound that damages DNA and impairs the body’s ability to repair this damage,” says Andrews. “This DNA damage can set the ...
Alcohol flush reaction is a condition in which an individual's face or body experiences flushes (appears red) or blotches as a result of an accumulation of acetaldehyde, a metabolic byproduct of the catabolic metabolism of alcohol. It is best known as a condition that is experienced by people of Asian descent.
While red wine and white wine have similar nutrition profiles and alcohol contents, red wine has more antioxidants—the compounds responsible for most of its health benefits. “Red wine has ...
[4] [6] Alcohol dehydrogenase and aldehyde dehydrogenase are present at their highest concentrations (in liver mitochondria). [98] [107] But these enzymes are widely expressed throughout the body, such as in the stomach and small intestine. [2] Some alcohol undergoes a first pass of metabolism in these areas, before it ever enters the ...
"A simple mouth swab is all we need to find out whether you have inherited DNA changes that affect your ability to metabolize alcohol and may increase your risk of serious health complications ...
Alcohol intolerance is an inherited genetic disorder that impairs alcohol metabolism. [34] The increased accumulation of acetaldehyde in affected individuals due to deficient aldehyde dehydrogenase enzymes often leads to the characteristic symptom of having flushed skin.
The health benefits of a modest alcohol consumption reported in people of European descent appear not to exist among people of African descent. [18] Higher body masses and the prevalence of high levels of alcohol dehydrogenase in an individual increase alcohol tolerance, and both adult weight and enzymes vary with ethnicity.