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All of these drugs inhibit the gastric H,K-ATPase by covalent binding, so the duration of their effect is longer than expected from their levels in the blood. [ 74 ] Targeting the terminal step in acid production, as well as the irreversible nature of the inhibition, results in a class of medications that are significantly more effective than H ...
dexamethasone – anti-inflammatory steroid. diazepam – benzodiazepine used to treat status epilepticus, also used as a preanaesthetic and a sedative. dichlorophene – fungicide, germicide, and antimicrobial agent, also used for the removal of parasites. diphenhydramine – histamine blocker. doxycycline – antibiotic, also used to treat ...
Rabeprazole, sold under the brand name Aciphex, among others, is a medication that decreases stomach acid. [6] It is used to treat peptic ulcer disease, gastroesophageal reflux disease, and excess stomach acid production such as in Zollinger–Ellison syndrome. [6]
Proton-pump inhibitors (PPIs) are a group of drugs whose main action is a pronounced and long-lasting reduction of gastric acid production. They are the most potent inhibitors of acid secretion available. The group followed and has largely superseded another group of pharmaceuticals with similar effects, but a different mode of action, called H ...
Omeprazole, sold under the brand names Prilosec and Losec, among others, is a medication used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger–Ellison syndrome. [1] It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. [1]
Pantoprazole, sold under the brand name Protonix, among others, is a medication used for the treatment of stomach ulcers, short-term treatment of erosive esophagitis due to gastroesophageal reflux disease (GERD), maintenance of healing of erosive esophagitis, and pathological hypersecretory conditions including Zollinger–Ellison syndrome. [ 5 ...
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