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  2. Male breast cancer - Wikipedia

    en.wikipedia.org/wiki/Male_breast_cancer

    The study also found that: a) men treated with adjuvant radiotherapy (i.e. radiotherapy in addition to other treatments) had significantly higher 5 year overall survival rates than men not treated with radiation therapy (59.4% v.s. 44.5%, respectively); b) Tamoxifen therapy improved overall survival rates compared to treatments not using ...

  3. Gender-affirming hormone therapy - Wikipedia

    en.wikipedia.org/wiki/Gender-affirming_hormone...

    Gender-affirming hormone therapy (GAHT), also called hormone replacement therapy (HRT) or transgender hormone therapy, is a form of hormone therapy in which sex hormones and other hormonal medications are administered to transgender or gender nonconforming individuals for the purpose of more closely aligning their secondary sexual characteristics with their gender identity.

  4. Selective estrogen receptor modulator - Wikipedia

    en.wikipedia.org/wiki/Selective_estrogen...

    Tamoxifen is more promiscuous than raloxifene in target sites because of the relationship between ER's amino acid in Asp-351 and the antiestrogenic side chain of the SERM. The side chain for tamoxifen cannot neutralize Asp-351, so the site allosterically influences AF-1 at the proximal end of the ER. This issue is mended with the second ...

  5. Masculinizing hormone therapy - Wikipedia

    en.wikipedia.org/wiki/Masculinizing_hormone_therapy

    The study found that transgender men have a >4-fold and 2-fold increased odds of having a myocardial infarction when compared with cisgender women and cisgender men, respectively. [7] Though it is not always the case, [ 2 ] [ 8 ] testosterone for transmasculine people is often intended to be used long-term.

  6. Dutasteride - Wikipedia

    en.wikipedia.org/wiki/Dutasteride

    [2] [3] Its elimination half-life is increased in the elderly (170 hours for men aged 20–49 years, 300 hours for men aged >70 years). [1] No dosage adjustment is necessary in the elderly nor in patients with renal impairment. [1] Because of its long elimination half-life, dutasteride requires 5 to 6 months to reach steady-state concentrations ...

  7. Late-stage breast cancer is rising, especially among Black ...

    www.aol.com/stage-breast-cancer-rising...

    The study, which looked at data from 2004 to 2021, found that advanced breast cancer rates have risen among women of all ages, with the sharpest increases in young women aged 20 to 39, and women ...

  8. Toremifene - Wikipedia

    en.wikipedia.org/wiki/Toremifene

    Toremifene appears to be safer than tamoxifen. [15] It has a lower risk of venous thromboembolism (VTE) (e.g., pulmonary embolism), stroke, and cataracts. [15] The lower risk of VTE may be related to the fact tamoxifen decreases levels of the antithrombin III to a significantly greater extent than either 60 or 200 mg/day toremifene. [15]

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