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2. Antiestrogen - Wikipedia

   en.wikipedia.org/wiki/Antiestrogen

   Antiestrogens include selective estrogen receptor modulators (SERMs) like tamoxifen, clomifene, and raloxifene, the ER silent antagonist and selective estrogen receptor degrader (SERD) fulvestrant, [6] [7] aromatase inhibitors (AIs) like anastrozole, and antigonadotropins including androgens/anabolic steroids, progestogens, and GnRH analogues.

3. Selective estrogen receptor modulator - Wikipedia

   en.wikipedia.org/wiki/Selective_estrogen...

   Tamoxifen is a pure antiestrogenic trans-isomer and has differential actions at estrogen target tissues throughout the body. Tamoxifen is selectively antiestrogenic in the breast but estrogen-like in bones and endometrial cancer. [24] Tamoxifen undergo phase I metabolism in the liver by microsomal cytochrome P450 (CYP) enzymes.

4. Dutasteride - Wikipedia

   en.wikipedia.org/wiki/Dutasteride

   [2] [3] Its elimination half-life is increased in the elderly (170 hours for men aged 20–49 years, 300 hours for men aged >70 years). [1] No dosage adjustment is necessary in the elderly nor in patients with renal impairment. [1] Because of its long elimination half-life, dutasteride requires 5 to 6 months to reach steady-state concentrations ...

5. Exemestane - Wikipedia

   en.wikipedia.org/wiki/Exemestane

   Any circulating estrogen in post-menopausal women as well as men is the result of estrogen escaping local metabolism and entering the circulatory system. [ 12 ] Exemestane is an irreversible, steroidal aromatase inactivator of type I, structurally related to the natural substrate 4-androstenedione .

6. Gender-affirming hormone therapy - Wikipedia

   en.wikipedia.org/wiki/Gender-affirming_hormone...

   Gender-affirming hormone therapy (GAHT), also called hormone replacement therapy (HRT) or transgender hormone therapy, is a form of hormone therapy in which sex hormones and other hormonal medications are administered to transgender or gender nonconforming individuals for the purpose of more closely aligning their secondary sexual characteristics with their gender identity.

7. Retiree Mental Health Crisis: The Best & Worst States for ...

   www.aol.com/retiree-mental-health-crisis-best...

   Every generation views their health and wellness differently. For older Americans, mental health diagnoses are becoming more prevalent. Between 2019 and 2023, the 65+ age group collectively ...

8. Masculinizing hormone therapy - Wikipedia

   en.wikipedia.org/wiki/Masculinizing_hormone_therapy

   The study found that transgender men have a >4-fold and 2-fold increased odds of having a myocardial infarction when compared with cisgender women and cisgender men, respectively. [7] Though it is not always the case, [ 2 ] [ 8 ] testosterone for transmasculine people is often intended to be used long-term.

9. Late-stage breast cancer is rising, especially among Black ...

   www.aol.com/stage-breast-cancer-rising...

   The study, which looked at data from 2004 to 2021, found that advanced breast cancer rates have risen among women of all ages, with the sharpest increases in young women aged 20 to 39, and women ...