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Histopathology of localized TGCT arising in hand finger. H&E stain. Localized TGCT is sometimes referred to as localized pigmented villonodular synovitis (L-PVNS), giant cell tumor of the tendon sheath (GCT-TS), nodular tenosynovitis, localized nodular tenosynovitis, and L-TGCT. [2]: 1 [3]: 100 The localized form of TGCT is more common.
Zinc finger protein 91 homolog is a protein that in humans is encoded by the ZFP91 gene. [5] [6] The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2 type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins.
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase .
100507290 319748 Ensembl ENSG00000261221 ENSMUSG00000074405 UniProt P0CJ78 Q3U3I9 RefSeq (mRNA) NM_001195605 NM_001033383 NM_001290426 RefSeq (protein) NP_001182534 NP_001028555 NP_001277355 Location (UCSC) Chr 19: 55.61 – 55.62 Mb Chr 7: 5.02 – 5.04 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse ZNF865 (also referred to as BLST [2-4]) is a C2H2 member of the zinc finger family ...
The role of zinc finger protein as transcription factors can be utilized to target genes to participate in the removal of SARS infection. The drug that is predicted to be able to target ZFP62 is named Artenimol , which would inhibit the RNA-dependent RNA polymerase activity of ZFP62, which is known to be an effective mechanism of other COVID-19 ...
The KRAB domain had initially been identified in 1988 as a periodic array of leucine residues separated by six amino acids 5’ to the zinc finger region of KOX1/ZNF10 [7] coined heptad repeat of leucines (also known as a leucine zipper). [8] Later, this domain was named in association with the C2H2-Zinc finger proteins Krüppel associated box ...
84676 433766 Ensembl ENSG00000158022 ENSMUSG00000028834 UniProt Q969Q1 Q38HM4 RefSeq (mRNA) NM_032588 NM_001039048 NM_001369245 RefSeq (protein) NP_115977 n/a Location (UCSC) Chr 1: 26.05 – 26.07 Mb Chr 4: 134.04 – 134.06 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse E3 ubiquitin-protein ligase TRIM63, also known as "MuRF1" (Muscle Ring-Finger Protein-1), is an enzyme that in ...
2735 14632 Ensembl ENSG00000111087 ENSMUSG00000025407 UniProt P08151 P47806 RefSeq (mRNA) NM_001160045 NM_001167609 NM_005269 NM_010296 RefSeq (protein) NP_001153517 NP_001161081 NP_005260 NP_034426 Location (UCSC) Chr 12: 57.46 – 57.47 Mb Chr 10: 127.17 – 127.18 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Zinc finger protein GLI1 also known as glioma-associated oncogene is a ...