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A Duloxetine recall by the FDA has flagged more than 7,100 bottles of the Cymbalta generic drug due to a cancerous chemical. ... their health care professionals about concerns and other treatment ...
Duloxetine, sold under the brand name Cymbalta among others, [1] is a medication used to treat major depressive disorder, generalized anxiety disorder, obsessive-compulsive disorder, fibromyalgia, neuropathic pain and central sensitization.
Effects of chloro, methoxy and trifluoromethyl substituents in the aromatic ring of cycloalkanol ethylamine scaffold were tested. The results showed that the strongest electron-withdrawing m -trifluoromethyl analogue exhibited the most potent inhibitory effect of norepinephrine and the most selectivity over serotonin uptake. [ 36 ]
To avoid drug interactions, your healthcare provider will tell you which process to use and how to switch from one antidepressant to another safely based on your medications and overall health.
The FDA has recalled thousands of bottles of the antidepressant duloxetine, sold under brand name Cymbalta, due to the presence of a possibly cancer-causing chemical.
[181] [182] Discontinuation effects appear to be less for fluoxetine, perhaps owing to its long half-life and the natural tapering effect associated with its slow clearance from the body. One strategy for minimizing SSRI discontinuation symptoms is to switch the patient to fluoxetine and then taper and discontinue the fluoxetine.
It’s normal for your weight to fluctuate by a small amount from day to day, and minor changes in your weight shouldn’t be seen as a sign that your antidepressant is causing you to gain weight.
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.